Protein Alignment babo and acvr2ba

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_571285.1
• Gene: acvr2ba / 30457
• ZFINID: ZDB-GENE-980526-549
• Length: 509
• Species: Danio rerio
• Alignment Length: 539
• Identity: 169/539 - (31%)
• Similarity: 252/539 - (46%)
• Gaps: 106/539 - (19%)

  Fly   111 LPIYIAQPSAKKPENKIKCHC----------DTCKESNNICETD----GFCFTSVEKNSDGSIIF 161
            |..:.|.||..:.|.:   .|          .|.:.....||.:    ..|:.|...|| |||
Zfish    12 LATFAADPSHGEVETR---ECLYYNVNWEVEKTNRSGVERCEGEKDKRSHCYASWRNNS-GSI-- 70

  Fly   162 SYRCLHKSQIFPPGRSIWCND----------GLHGGPTARPVGRNGAHACCKDRDFCNRFLWPKT 216
                    |:...|  .|.:|          .....|.        ...||.:.:|||
Zfish    71 --------QLVKKG--CWLDDFNCYDRQECVATEENPQ--------VFFCCCEGNFCN------- 110

  Fly   217 KDQRSDRVEE--GRQISVQDYVPHRLTSWEFVAI---ILGATLFICFTGTSTWYYCQRRKRMASG 276
              :|...:.:  |..||.....|..|....:..:   :|...:.:.|     |.|  |.::...|
Zfish   111 --ERFTHLPDISGPVISPPPVSPSLLNVLVYSLLPLSMLSMAVLLAF-----WMY--RHRKPPYG 166

  Fly   277 RTFAKEDSAYDPILNGNTTIHDIIEMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRG 341
            .....||....|                 .|...||         :.:||..|..:||||.||:.
Zfish   167 HVDVNEDPGPSP-----------------PSPLVGL---------KPLQLLEVKARGRFGCVWKA 205

  Fly   342 RWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGS 406
            :...|.||||||..:::.||..|.|::.|..::|:|:|.||||:.:.:....:.||:|::||.||
Zfish   206 QMINEYVAVKIFPIQDKLSWQNEREMFSTPGMKHDNLLRFIAAEKRGSNLEMEFWLITEFHERGS 270

  Fly   407 LFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRG---KPAIAHRDLKSKNILVKSNLSCAI 468
            |.|||..:.|....:..::.|:|.|||:||.|:..::|   ||||||||.||||:::|.:|:..|
Zfish   271 LTDYLKGNAVSWADLCVIAESMACGLAYLHEDVPRSKGEGPKPAIAHRDFKSKNVMLKMDLTAVI 335

  Fly   469 GDLGLAVRHVEKNDSVDIPSTH-RVGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLILWEIAR 532
            ||.|||||........|   || :|||:||||||||:.::|.|. ||:.|.|:||.||:|||:..
Zfish   336 GDFGLAVRFEPGKPPGD---THGQVGTRRYMAPEVLEGAINFQR-DSFLRIDMYAMGLVLWELVS 396

  Fly   533 RCNM--GMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWY 595
            ||..  |.: |||.||:.:.:...||:|:::..|..:|.||...:.|.....|..|.:.|:|||.
Zfish   397 RCKAADGPV-DEYMLPFEEEIGQHPSLEDLQDAVVHKKLRPAFKDCWLKHSGLCQMCETMEECWD 460

  Fly   596 PNPVARLTALRIKKTLASI 614
            .:..|||:|..:::.::.|
Zfish   461 HDAEARLSAGCVQERISQI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	20/106 (19%)
		GS	294..324	CDD:197743	3/29 (10%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	123/293 (42%)
acvr2ba	NP_571285.1	TFP_LU_ECD_ACVR2B	26..116	CDD:467152	22/122 (18%)
		STKc_ACVR2b	192..482	CDD:271042	123/293 (42%)