Protein Alignment babo and Acvr1c

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001104500.1
• Gene: Acvr1c / 269275
• MGIID: 2661081
• Length: 493
• Species: Mus musculus
• Alignment Length: 498
• Identity: 259/498 - (52%)
• Similarity: 339/498 - (68%)
• Gaps: 34/498 - (6%)

  Fly   127 IKCHCDTCKESNNICETDGFCFTSVE-KNSDGSIIFSYRCLHKSQIFPPGRSIWCNDGLHGGPTA 190
            :||.|..|..||..|:|:|.|:.||. .|....:|.|  |:...::   ...::|:...:...|
Mouse    26 LKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKS--CVSLPEL---NAQVFCHSSNNVTKT- 84

  Fly   191 RPVGRNGAHACCKDRDFCNRF-LWPKTKDQRSDRVEEGRQISVQDYVPHRLTSWEFVAIILGATL 254
                     .|| ..||||.. |...|....:.|:.. .:::|...||..|.|   :|.:|  |:
Mouse    85 ---------ECC-FTDFCNNITLHLPTASPNAPRLGP-TELTVVITVPVCLLS---IAAML--TI 133

  Fly   255 FICFTGTSTWYYCQRRKRMASGRTFAKEDSAYDPILNGNTTIHDII-EMTTSGSGSAGLPLLVQR 318
            :.|.....|:...:|..        .:|..|...::|...|:.|:| :.|.||||| ||||||||
Mouse   134 WACQDRQCTYRKTKRHN--------VEEALAEYSLVNAGKTLKDLIYDATASGSGS-GLPLLVQR 189

  Fly   319 SIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 383
            :|||.:.|..::|||||||||.|||.||:|||||||||:|.||||||||||||||||||||||||
Mouse   190 TIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIA 254

  Fly   384 ADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAI 448
            |||||||||||||||::|||.|||:|||..:.|....|:.::||||:|||||||:||||:|||||
Mouse   255 ADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMVKLALSIASGLAHLHMEIVGTQGKPAI 319

  Fly   449 AHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFD 513
            ||||:||||||||...:|||.||||||:|....:::|||...:||||||||||:||::||...|:
Mouse   320 AHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNLSIFE 384

  Fly   514 SYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWH 578
            |:||||:|:.||:.|||||||::|.:.:||||||||:|..|||||||:||||.:|.|||:||:|.
Mouse   385 SFKRADIYSVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQ 449

  Fly   579 ASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVK 621
            :.:.|..|.::|:||||.|..|||||||:|||::.:.|::..|
Mouse   450 SCEALRVMGRIMRECWYANGAARLTALRVKKTISQLCVKEDCK 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	23/83 (28%)
		GS	294..324	CDD:197743	20/30 (67%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	195/286 (68%)
Acvr1c	NP_001104500.1	TFP_LU_ECD_ALK7	27..99	CDD:467070	25/87 (29%)
		TGF_beta_GS	166..193	CDD:462503	18/27 (67%)
		STKc_TGFbR1_ACVR1b_ACVR1c	199..486	CDD:271045	195/286 (68%)