Protein Alignment babo and Acvr1c

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_620790.2
• Gene: Acvr1c / 245921
• RGDID: 621789
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 255/505 - (50%)
• Similarity: 333/505 - (65%)
• Gaps: 48/505 - (9%)

  Fly   127 IKCHCDTCKESNNICETDGFCFTSVE-KNSDGSIIFSYRCLHKSQIFPPGRSIWCNDGLHGGPTA 190
            :||.|..|..||..|:|:|.|:.||. .|....:|.|  |:...::   ...::|:...:...|
  Rat    26 LKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKS--CVSLPEL---NAQVFCHSSNNVTKT- 84

  Fly   191 RPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVP------HRLTSWEFVAII 249
                     .|| ..||||                     ::..::|      .||...|...:|
  Rat    85 ---------ECC-FTDFCN---------------------NITLHLPTASPDAPRLGPTELTVVI 118

  Fly   250 LGATLFICFTGTSTWYYCQRRK--RMASGRTFAKEDSAYDPILNGNTTIHDII-EMTTSGSGSAG 311
            ......:......|.:.||.|:  ...:.|...:|..|...::|...|:.|:| :.|.||||| |
  Rat   119 TVPVCLLSIAAMLTIWACQDRQCTYRKTKRHNVEEPLAEYSLVNAGKTLKDLIYDATASGSGS-G 182

  Fly   312 LPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHE 376
            |||||||:|||.:.|..::|||||||||.|||.||:|||||||||:|.|||||||||||||||||
  Rat   183 LPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHE 247

  Fly   377 NILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVG 441
            ||||||||||||||||||||||::|||.|||:|||..:.|....|:.::||||:|||||||:|||
  Rat   248 NILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMVKLALSIASGLAHLHMEIVG 312

  Fly   442 TRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDES 506
            |:|||||||||:||||||||...:|||.||||||:|....:::|||...:||||||||||:||::
  Rat   313 TQGKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDT 377

  Fly   507 MNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRP 571
            ||...|:|:||||:|:.||:.|||||||::|.:.:||||||||:|..|||||||:||||.:|.||
  Rat   378 MNVNIFESFKRADIYSVGLVYWEIARRCSVGGLVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRP 442

  Fly   572 NIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVK 621
            |:||:|.:.:.|..|.::|:||||.|..|||||||:|||::.:.|::..|
  Rat   443 NLPNQWQSCEALRVMGRIMRECWYANGAARLTALRVKKTISQLCVKEDCK 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	23/83 (28%)
		GS	294..324	CDD:197743	20/30 (67%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	195/286 (68%)
Acvr1c	NP_620790.2	TFP_LU_ECD_ALK7	25..99	CDD:467070	24/109 (22%)
		TGF_beta_GS	166..193	CDD:462503	18/27 (67%)
		STKc_TGFbR1_ACVR1b_ACVR1c	199..486	CDD:271045	195/286 (68%)