Protein Alignment babo and acvrl1

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_002935162.2
• Gene: acvrl1 / 100493282
• XenbaseID: XB-GENE-484224
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 229/510 - (44%)
• Similarity: 311/510 - (60%)
• Gaps: 49/510 - (9%)

  Fly   124 ENKIK------CHCDTCKESNNICETDGFCFTSVEKNSDGSIIFSYRCLHKSQIFPPGRSIWCND 182
            |:|.|      |:|:....|...| ....|:.:....|:...|...:....:.|.....|:..|.
 Frog    30 EDKTKGSKYWTCYCNDASCSGETC-VGRVCYVTESYASESEGISRAKGCFNNSIKEHCSSLMSNL 93

  Fly   183 GLHGGPTARPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVPHRLTSWEFVA 247
            ..|               || :.||||:           |:|   ..:::...:...|......:
 Frog    94 KEH---------------CC-EWDFCNK-----------DKV---LNVTINPSLVTLLLVTVLPS 128

  Fly   248 IILGATLFICFTGTSTWYY---CQRRKR-MASGRTFAKEDSAYDPILNGNTTIHDII-EMTTSGS 307
            :|....||:..    .|.|   ..||.| :|....|...|.....:: |::|:.:.: |..|:||
 Frog   129 VIFIVILFLVI----AWIYKAKLHRRNRLLAMPSDFDDADMLKASVV-GDSTLGEFLDEYCTTGS 188

  Fly   308 GSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVM 372
            || |||.||||::|||:.|...:||||:||||||.|:||||||||||||:|.|||||.|||.||:
 Frog   189 GS-GLPFLVQRTVARQITLVECVGKGRYGEVWRGTWQGENVAVKIFSSRDEQSWFRETEIYNTVL 252

  Fly   373 LRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHM 437
            |||||||||||:|.....:.|||||:|.||::|||:|||....||:...|.::|||..||.|||:
 Frog   253 LRHENILGFIASDMTSRNSSTQLWLITHYHDDGSLYDYLQRTSVDSEGCLKLALSIICGLVHLHV 317

  Fly   438 DIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEV 502
            :|.||:||.|||||||||:|||||:|..|.|.||||||.|.:..|.:||.:..||||||||||||
 Frog   318 EIFGTQGKAAIAHRDLKSRNILVKANKQCCIADLGLAVMHSQNGDYLDIGNNPRVGTKRYMAPEV 382

  Fly   503 LDESMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIE 567
            |||::....|:|||:.|::|:||:||||.||..:..:.::|:.|::|||..|||.|:|:|||||:
 Frog   383 LDETIRTDSFESYKQTDLWAYGLVLWEICRRTVVNGMVEDYRPPFFDVVPHDPSFEDMRKVVCID 447

  Fly   568 KCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASI-SVEDKVK 621
            :.||||.|.|.:.::|..|.|:|:|||:.:|.||||||||||||..: |..|::|
 Frog   448 QQRPNISNTWSSDNILSAMTKIMRECWFSSPSARLTALRIKKTLNKLRSSLDQIK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	17/88 (19%)
		GS	294..324	CDD:197743	16/30 (53%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	173/287 (60%)
acvrl1	XP_002935162.2	TFP_LU_ECD_ALK1	38..106	CDD:467064	17/95 (18%)
		TGF_beta_GS	175..202	CDD:462503	14/27 (52%)
		STKc_ACVR1_ALK1	198..494	CDD:271044	178/295 (60%)