Protein Alignment babo and tgfbr2a

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_073787446.1
• Gene: tgfbr2a / 100334928
• ZFINID: ZDB-GENE-120404-1
• Length: 659
• Species: Danio rerio
• Alignment Length: 532
• Identity: 157/532 - (29%)
• Similarity: 249/532 - (46%)
• Gaps: 107/532 - (20%)

  Fly   126 KIKCHCDTCKESNNICETDGFCFTSVEKNSDGSIIFSYRCLHKSQIFPPGRSIWCNDGLHGGPTA 190
            ::|.:|..|...:::|...|.|.::...||        .|....::.   .|.|.::|  |..:.
Zfish   148 RLKQNCKFCDVESSVCNASGVCESACGINS--------ICETPDEVC---ASAWRSNG--GNSSI 199

  Fly   191 RPVGRNGA-------------------------HAC------CKDRDFCNRFLWPKTKDQRSDRV 224
            ..|..|.|                         :.|      |.||.|.|..|
Zfish   200 ETVCHNPALLFHGHNLTDSQSRVCQMRRVEEDLYICSCNDEECNDRLFFNHDL------------ 252

  Fly   225 EEGRQISVQDYVPHRLTSWEFVAIILGATLFICFTGTSTWYYC----QRRKRMASGRTFAKE--- 282
               :|.....:.|...:||..:|.:|.:...:......:.:||    |.:.::.:.::...|
Zfish   253 ---KQYPGVQFDPPSESSWFSLAPVLISVFVLIPIVLLSVFYCYHISQHKLKLPNKKSLDSERCN 314

  Fly   283 ---------DSAYDPILNGNTTIHDIIEMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEV 338
                     ||:   .:|.|:..|: .|:         ||          :||..|:|||||.:|
Zfish   315 IFMNPEEHSDSS---SINANSLNHN-TEL---------LP----------IQLDRVVGKGRFADV 356

  Fly   339 WRGRWRG-----ENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLV 398
            ::.:.:.     :.||||||...|..||..|.:|:..|.|||||:|.|:.|:.:.  ...|.||:
Zfish   357 YKAKLKQSADSFQTVAVKIFPYEEFSSWKSEWQIFSDVELRHENVLQFLTAEERT--AERQYWLI 419

  Fly   399 TDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGT-RGKPAIAHRDLKSKNILVKS 462
            |.|||.|:|.:.|....:....|..:.:|:|.|:||||.|.... |.|.:||||||||.|:||||
Zfish   420 TAYHERGNLQELLALQVIGWEEMCRLGVSLARGVAHLHSDRTPCGRAKVSIAHRDLKSSNVLVKS 484

  Fly   463 NLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLIL 527
            :.||.:.|.||::|........::.::.:|||.||||||||:..|:.::.:|:|:||||:..|:|
Zfish   485 DWSCCVCDFGLSLRLDSCLSPEELANSGQVGTARYMAPEVLESRMDLENTESFKQADVYSMALVL 549

  Fly   528 WEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKE 592
            |||..||:......:|: |.:..::..|.:|.||..|..::.||.||..|.....:|:::..::|
Zfish   550 WEIMSRCSATGDVRDYE-PPFGKLKGHPCVESMKDDVIRDRLRPEIPTSWSKHAGVHHLSSTIEE 613

  Fly   593 CWYPNPVARLTA 604
            ||..:|.|||||
Zfish   614 CWDHDPEARLTA 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	21/113 (19%)
		GS	294..324	CDD:197743	4/29 (14%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	114/283 (40%)
tgfbr2a	XP_073787446.1	None