Protein Alignment babo and acvr1c

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_021334502.1
• Gene: acvr1c / 100331105
• ZFINID: ZDB-GENE-181207-1
• Length: 491
• Species: Danio rerio
• Alignment Length: 505
• Identity: 249/505 - (49%)
• Similarity: 338/505 - (66%)
• Gaps: 47/505 - (9%)

  Fly   127 IKCHCDTCKESNNICET--DGFCFTSVEK-NSDGSIIFSYRCLHKSQIFPPGRSIWCNDGLHGGP 188
            :||.|..|  .|:.|||  :|.|:.||.. |.....:.|  |:..|::  .|: ::|..
Zfish    23 LKCVCHLC--VNHTCETEAEGACWNSVMLINGKEETVKS--CVSPSEL--KGQ-VFCYS------ 74

  Fly   189 TARPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVPHRLTSW---EFVAIIL 250
                 .||.:...|...||||                 ...:.:....|...:.|   |..|:||
Zfish    75 -----SRNVSKRNCCFTDFCN-----------------NETLHLNPEQPPEDSGWSQLEVAAVIL 117

  Fly   251 GATLFICFTGTSTWYYCQRRKRMASGRTFAK--EDSAYDP-ILNGNTTIHDII-EMTTSGSGSAG 311
            ..:..:| .|........:..|....::..:  |:...|| :::.:..:.::| :|:|||||| |
Zfish   118 VPSCLVC-VGVMLGVCAIQNLRCTHIKSLKQDPEEPLDDPTLVSPDKCLKELIYDMSTSGSGS-G 180

  Fly   312 LPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHE 376
            |||||||:|||.:.|...||||||||||||:||||:|||||||||:|.|||||||||||:||||:
Zfish   181 LPLLVQRTIARTIVLQETIGKGRFGEVWRGKWRGEDVAVKIFSSRDERSWFREAEIYQTIMLRHD 245

  Fly   377 NILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVG 441
            ||||||||||||||:|||||||::|||:|||||||....|....|:.::||||:|:|||||:|:|
Zfish   246 NILGFIAADNKDNGSWTQLWLVSEYHEHGSLFDYLNRFTVSVEGMIVLALSIASGIAHLHMEIIG 310

  Fly   442 TRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDES 506
            |:|||||||||:||||||||.|.:..|.||||||:|....:::|||..||||||||||||:||:|
Zfish   311 TQGKPAIAHRDIKSKNILVKKNGAAVIADLGLAVKHDSNTNTIDIPINHRVGTKRYMAPEILDDS 375

  Fly   507 MNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRP 571
            :|...|:|:||||:|:..|:.||:||||::..|::::||||||.||.|||:::|::|||.:|.||
Zfish   376 INMSSFESFKRADIYSLSLVFWELARRCSIQGIHEDFQLPYYDQVQSDPSLDDMRRVVCEQKLRP 440

  Fly   572 NIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVK 621
            ||||:|.:.:.|..|.|:|:|||:.||.|||||||:|||::.::|...||
Zfish   441 NIPNQWQSCEALRVMGKIMRECWHANPAARLTALRVKKTISQVTVVKDVK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	24/85 (28%)
		GS	294..324	CDD:197743	19/30 (63%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	189/286 (66%)
acvr1c	XP_021334502.1	TFP	22..96	CDD:480272	25/107 (23%)
		TGF_beta_GS	165..191	CDD:462503	17/26 (65%)
		STKc_TGFbR1_ACVR1b_ACVR1c	197..483	CDD:271045	189/285 (66%)