| Sequence 1: | NP_610430.1 | Gene: | CG13748 / 35896 | FlyBaseID: | FBgn0033355 | Length: | 113 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001019978.1 | Gene: | APLP1 / 333 | HGNCID: | 597 | Length: | 651 | Species: | Homo sapiens |
| Alignment Length: | 28 | Identity: | 8/28 - (28%) |
|---|---|---|---|
| Similarity: | 14/28 - (50%) | Gaps: | 8/28 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 67 GVCRAL-------IPRWRYDPEQ-KKCV 86 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG13748 | NP_610430.1 | Kunitz-type | 57..112 | CDD:444694 | 8/28 (29%) |
| APLP1 | NP_001019978.1 | A4_EXTRA | 46..211 | CDD:128326 | 8/28 (29%) |
| GFLD subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01217 | 50..146 | 8/28 (29%) | |||
| CuBD subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01217 | 154..212 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 214..287 | ||||
| APP_E2 | 285..467 | CDD:463752 | |||
| O-glycosylated at three sites | 285..305 | ||||
| Heparin-binding. /evidence=ECO:0000250 | 310..342 | ||||
| Heparin-binding. /evidence=ECO:0000250 | 410..441 | ||||
| Collagen-binding. /evidence=ECO:0000250 | 442..459 | ||||
| JMTM_APLP1 | 565..649 | CDD:411991 | |||
| Basolateral sorting signal. /evidence=ECO:0000250 | 605..616 | ||||
| Interaction with DAB1. /evidence=ECO:0000250 | 633..650 | ||||
| Interaction with DAB2. /evidence=ECO:0000250 | 637..651 | ||||
| Clathrin-binding. /evidence=ECO:0000255 | 641..644 | ||||
| NPXY motif, contains endocytosis signal | 641..644 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||