Protein Alignment PAN2 and isg20l2

DIOPT Version :10

• Sequence 1: NP_610427.2
• Gene: PAN2 / 35893
• FlyBaseID: FBgn0033352
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_001096663.1
• Gene: isg20l2 / 558447
• ZFINID: ZDB-GENE-070928-8
• Length: 321
• Species: Danio rerio
• Alignment Length: 257
• Identity: 71/257 - (27%)
• Similarity: 107/257 - (41%)
• Gaps: 44/257 - (17%)

  Fly   991 SSSGSPTNLSNPFLEEIVSPMLGNLSADATLQPLQSDEMPQSGDLVAMDAEFVTLNPEENEIRPD 1055
            |||....:.::.:|    .|...|:|.....|.:.....|.....:|:|.|.|...|
Zfish    96 SSSAQAYSRTSTYL----FPSHANISQRDLTQRMAVPRPPGPIKYLALDCEMVGTGP-------- 148

  Fly  1056 GKTATIKPCHMSVARISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRL 1120
                  |.....:||.|.:...|..    ..|.|:.....|.||.|::|||:..||        |
Zfish   149 ------KGAQSELARCSIVSYDGDV----VYDKYVKPINPVTDYRTRWSGIRRQDL--------L 195

  Fly  1121 TALKYSYQKLKYLVDV--GVIFVGHGLKNDFRVINIYVPSEQIIDT--VHLFH----MPHHRMVS 1177
            .|..: |...|.:|.:  |.:.|||.:.|||:.:..:.|:.|..||  :.|.:    .|..:.||
Zfish   196 HATPF-YHAQKEIVKIITGKVVVGHAIHNDFKALKYFHPAFQTRDTSRIPLLNEKAGFPEKQCVS 259

  Fly  1178 LRFLAWHFLGTKIQS--ETHDSIEDARTTLQLYKHYLKLQEEKKFANALKNLYERGKQLQWK 1237
            |:.|....|...||:  ..|.|:|||:.|::|||...::.|:|.   |..||..:...|..|
Zfish   260 LKKLTQAILKRDIQTGYRGHSSVEDAKATMELYKVVERMWEQKL---ASLNLSAKAMDLAMK 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:475233
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:463872
		zf-CCCH_2	799..816	CDD:464217
		PAN2_exo	1036..1209	CDD:99846	53/182 (29%)
isg20l2	NP_001096663.1	ISG20	137..293	CDD:99852	53/182 (29%)