Protein Alignment PAN2 and prage

DIOPT Version :8

• Sequence 1: NP_610427.2
• Gene: PAN2 / 35893
• FlyBaseID: FBgn0033352
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_001188528.1
• Gene: prage / 31136
• FlyBaseID: FBgn0283741
• Length: 852
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 135/706 (19%)
• Similarity: 227/706 (32%)
• Gaps: 235/706 (33%)

  Fly   617 SSKNASTYSGSVQTSTNAEN-------AGSSETSGS----SDLYDSISDENSKEDDRERSKINAE 670
            :|.::...|..:.:|:...|       |||...||.    |..:...|.:.::..|....:..|.
  Fly   252 NSTSSDATSEDIDSSSELPNKSKGNSCAGSIHASGGSKSRSKRHQKQSGQQTRNPDHNGQRTGAA 316

  Fly   671 TDISKIFGTKQICINRCIKCQEEKIKESILLACNLSY----PNHIKDSDQYFNFGTILKRSLSSE 731
            |                 .|..:|.|:.     |..:    ||...::.|     ..:::.:..:
  Fly   317 T-----------------PCTGQKAKQG-----NAKWRQQQPNPSSNNQQ-----QQMQQQMQQQ 354

  Fly   732 KSIQAFCERCKKFSPTNQSVKVTSLPQILSINCGLNNEKDITFLKRQLNRCSEKTTVDAAASLST 796
            |       |.:...|...|..:...|   :.|.|               ..|::.|.|:::|.:.
  Fly   355 K-------RGRNKKPGKWSNNIIDNP---NSNHG---------------GSSQQKTCDSSSSSAL 394

  Fly   797 SKPCRYGANCSRSDCHFMHPDRKSP--SHTSQPNAVNNSPNGRQKSWFPLTFTMGINDQGEVQVQ 859
            |.|.......:.|          ||  |.||.|.|     ||.:|             :.|..::
  Fly   395 SSPTSSATTSATS----------SPTNSPTSYPRA-----NGNRK-------------RIEAALE 431

  Fly   860 TQSDASSGKS------------EQEEETEKPPTKGL-----DNN--RMYALHAVVCQVDDGTQKN 905
            .:.:...|:.            ||.|..:|...:.|     ||:  |:|..     .||....:.
  Fly   432 WRREQELGRQNANFLVPPLRQYEQLEFDDKTVVQQLRRHIIDNHLLRVYGF-----PVDSVVHEG 491

  Fly   906 LVSLINVQRPYHTM--KLAESAD-----------DPQSQWYIFNDFSISPVSPQESVWFTLDWKV 957
            .:.:.... |:.:.  .|||:|.           ..:::..:.|.......|||..
  Fly   492 AIEIFKCM-PHMSFAAALAETAQAVTVINYHDGLTNRAEEEVANSTDSGNSSPQSL--------- 546

  Fly   958 PCILFYRHVEDDSESASTTSSTVTESEETIPSESSSGSPT---------------NLSNP----- 1002
                       ||||....|.:..||..:  |.||:|...               :||.|
  Fly   547 -----------DSESGGEWSGSECESSNS--SSSSAGEAALGLELKYCHFVPVERSLSKPCARCK 598

  Fly  1003 ---FLEEIVSPMLG--------------------------NLSADATLQPLQSDEMPQSGDLVAM 1038
               .::|:....|.                          |...:::......|....||.:|.:
  Fly   599 RHFLVDELTGQYLTHEECQYHSGKYQRYYDGVSHGRWTCCNEGEESSPGCCLGDRHVWSGSVVGV 663

  Fly  1039 DAEFVT-LNPEENEIRPDGKTATIKPCHMS-------VARISCIRGQGPAEGVPFMDDYISTQEK 1095
            :..:.. :..|......|........|.||       |.::|.:    ...|....:.::.....
  Fly   664 NGPYYDFVRTEHRGSGEDEPAVYALDCEMSYTGRGLDVTKVSLV----ALNGQLVYEHFVRPVCD 724

  Fly  1096 VVDYLTQFSGIKPGDLDANFSKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQ 1160
            ::||.||:|||...||.:  ..|.|..::   :.|..|:....|.:||||:||.|.:.:.  ...
  Fly   725 IIDYNTQYSGITETDLCS--GAKSLAEVQ---RDLLQLITADTILIGHGLENDLRALRLV--HNT 782

  Fly  1161 IIDT----VHLFHMPHHRMVSLRFLAWHFLGTKIQ----SETHDSIEDARTTLQL 1207
            :|||    .|....|:.|  :||.|....|...||    :..|.|.||:|..::|
  Fly   783 LIDTSISFPHCNGFPYRR--ALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMEL 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:330360
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:315986	64/372 (17%)
		zf-CCCH_2	799..816	CDD:317060	2/17 (12%)
		PAN2_exo	1036..1209	CDD:99846	48/189 (25%)
prage	NP_001188528.1	PH-like	<614..650	CDD:302622	1/36 (3%)
		DnaQ	675..>837	CDD:223916	46/175 (26%)
		REX1_like	686..837	CDD:99848	45/164 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0847
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
	1	0.900