DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AIMP1 and Aimp1

DIOPT Version :9

Sequence 1:	NP_610426.2	Gene:	AIMP1 / 35892	FlyBaseID:	FBgn0033351	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_446209.1	Gene:	Aimp1 / 114632	RGDID:	620466	Length:	315	Species:	Rattus norvegicus

Alignment Length:	319	Identity:	151/319 - (47%)
Similarity:	206/319 - (64%)	Gaps:	15/319 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CKNYGQNCSKFARNKRTMADLQQIASNNERAEALINSIEAEISGIQQ----QLVERQKQELIKEN 73
            |:.:|    |.|.|...:..|:|   ....|:.:|..::.:::.:::    |...|::::|..||
  Rat     4 CRFWG----KMATNDAVLKRLEQ---KGAEADQIIEYLKQQVALLKEKAILQATLREEKKLQVEN 61

  Fly    74 AALAKEVEAALAQLVQLELRNGKKQIPVPGARGF---CTSAAPVVMPAEAGPATAAPAAPAPKPA 135
            |.|.||:|....:|:|.|:.||.||:|||.:...   |:.:..|...|.....|........|..
  Rat    62 AKLKKEIEELKQELIQAEIHNGVKQVPVPSSSSLETHCSVSESVTRSASVTTTTMTGGGGEEKKV 126

  Fly   136 KEPKEKKSKEKKPAAEKPAAAPEA-PVDVGRLDLRVGKIVEVGRHPDADSLYLEKIDCGEAAPRT 199
            ||..|||.::|:...:..||:.:: ||||.|||||:|.||...:||||||||:|::|.|||||||
  Rat   127 KEKTEKKGEKKEKKQQSAAASADSKPVDVSRLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRT 191

  Fly   200 VVSGLVKFVPLEEMQNRLVVVMCNLKPAKMRGVTSEAMVMCASTPEKVEVLSPPAGAVPGDLVHC 264
            ||||||..||||:||||:||::|||||||||||.|:|||||||:|||||:|:||.|:||||.:..
  Rat   192 VVSGLVNHVPLEQMQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILAPPNGSVPGDRITF 256

  Fly   265 EGYPRQPDAQLNPKKKIFESCAPDLKTNGELVACYKGAALHVPGKGNVVAQTLKNVNVK 323
            :.:|.:||.:|||||||:|...|||.||.|.||.||||...|.|||...|||:.|..:|
  Rat   257 DAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGAPFEVKGKGVCRAQTMANSGIK 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AIMP1	NP_610426.2	tRNA_bind_EMAP-II_like	161..262	CDD:239198	76/100 (76%)
Aimp1	NP_446209.1	Cnn_1N	<31..79	CDD:285263	13/47 (28%)
Aimp1	NP_446209.1	tRNA_bind_EMAP-II_like	153..255	CDD:239198	76/101 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350712
Domainoid	1	1.000	150	1.000	Domainoid score	I4293
eggNOG	1	0.900	-	-		E1_COG0143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31260
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2844
OMA	1	1.010	-	-		QHG56436
OrthoDB	1	1.010	-	-		D1434247at2759
OrthoFinder	1	1.000	-	-		FOG0000771
OrthoInspector	1	1.000	-	-		oto96154
orthoMCL	1	0.900	-	-		OOG6_100893
Panther	1	1.100	-	-	LDO	PTHR11586
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2386
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770