Protein Alignment AIMP1 and Yars1

DIOPT Version :10

• Sequence 1: NP_610426.2
• Gene: AIMP1 / 35892
• FlyBaseID: FBgn0033351
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_598912.5
• Gene: Yars1 / 107271
• MGIID: 2147627
• Length: 528
• Species: Mus musculus
• Alignment Length: 268
• Identity: 121/268 - (45%)
• Similarity: 154/268 - (57%)
• Gaps: 47/268 - (17%)

  Fly    68 ELIKENAA-------LAKEVEAALAQLVQLELRNGKKQIPVPGARGFCTSAAPVVMPAEAGPATA 125
            ||.|:.||       |...||.||.:|:.            |....|.|       ||....|:|
Mouse   294 ELEKDFAAEVVHPGDLKNSVEVALNKLLD------------PIREKFNT-------PALKKLASA 339

  Fly   126 APAAPAPKPAKEPKEKKSKEKKPAAEKPAAAPEAPVDV--GRLDLRVGKIVEVGRHPDADSLYLE 188
            |    .|.|:|:         ||.|:.||...| |.:|  .|||:|||||:.|.:||||||||:|
Mouse   340 A----YPDPSKQ---------KPPAKGPAKNSE-PEEVIPSRLDIRVGKILSVEKHPDADSLYVE 390

  Fly   189 KIDCGEAAPRTVVSGLVKFVPLEEMQNRLVVVMCNLKPAKMRGVTSEAMVMCAS---TPEKVEVL 250
            |||.|||.|||||||||:|||.||:|:|||||:|||||.|||||.|:.|::|||   ...:||.|
Mouse   391 KIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVDSQGMLLCASVEGVSRQVEPL 455

  Fly   251 SPPAGAVPGDLVHCEGYPR-QPDAQLNPKKKIFESCAPDLKTNGELVACYKGAALHVPGKGNVVA 314
            .||||:.||:.|..:||.: |||.:|.||||:||....|.|.:.|.:|.:|.... :...|.|..
Mouse   456 DPPAGSAPGERVFVQGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNF-MTKLGFVSC 519

  Fly   315 QTLKNVNV 322
            ::||..|:
Mouse   520 KSLKGGNI 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIMP1	NP_610426.2	DUF2968	<23..91	CDD:431707	11/29 (38%)
		PLN02610	<161..304	CDD:215329	87/148 (59%)
Yars1	NP_598912.5	nt_trans	8..328	CDD:469580	12/45 (27%)
		'HIGH' region. /evidence=ECO:0000250|UniProtKB:P54577	44..52
		'KMSKS' region. /evidence=ECO:0000250|UniProtKB:P54577	222..226
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:P54577	242..247
		PLN02610	<327..528	CDD:215329	109/223 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	339..363		12/37 (32%)