Protein Alignment Spt and Sry-alpha

DIOPT Version :10

• Sequence 1: NP_610423.3
• Gene: Spt / 35889
• FlyBaseID: FBgn0033348
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_524580.1
• Gene: Sry-alpha / 43571
• FlyBaseID: FBgn0003510
• Length: 530
• Species: Drosophila melanogaster
• Alignment Length: 610
• Identity: 195/610 - (31%)
• Similarity: 315/610 - (51%)
• Gaps: 115/610 - (18%)

  Fly     1 MEILRTKLEACLLILNRNNAAAAN--WLNDLCAVLLEFATLAHS---SFCSQGQSECSELVCLCL 60
            ||.|..:|..|..::....::..|  |||:.||..|:||:...:   .....|.:...|.:.|||
  Fly     1 MEQLLAQLHTCSELIAEGYSSTGNIGWLNEFCATFLDFASDLKARLPEVAPSGANLDVETIFLCL 65

  Fly    61 SQIMICIRQVENTMKLECGTTVSVSHQYFLDRIRWCLKRLMHLYSEESSSEAVAP-----ERSFL 120
            :|::.||..:|.|:.:|   ...::.|:||||:.|||:||  |.|.......|.|     :.||:
  Fly    66 TQVVTCITHLERTISME---APHMTRQHFLDRLDWCLRRL--LVSLTQLEGNVTPVKNLEDHSFV 125

  Fly   121 KLVDGALDCLAQF----------TSHSEENTDTSNCPKTPKEVLPLSQKLRANIDLILGQSLGFA 175
            :|:|.|||.|..:          :.|..|.:.|.:           :.:|.:.::.|:..:|.||
  Fly   126 ELMDLALDHLDDYMEKLAQQRNNSLHILEESFTED-----------TYQLASIVNHIVRHALAFA 179

  Fly   176 NVALSQDKRALSALCQKVIRECNAFQEECKESFSANYLSTLKLRAMTMEQAIYQLEDFINDALLR 240
            |||:..||:||:|||:.::.||..|.||..|..|.:    .||.|:::|:|:|.||.|:|:|||.
  Fly   180 NVAIHSDKKALTALCETLLAECATFHEEAGEPNSGH----RKLEALSLERALYALESFLNEALLH 240

  Fly   241 LVFTCFLDFEKFSVDKIRALLRNSPDNDDLADEFIADFDVNIDRATQIGIFAISFAPNLKMKTIM 305
            |:|...:|.|..||:|::..|:..|..   |.|.|:.||.|:||..|||:.||:|:.::|.|||:
  Fly   241 LLFVSLIDLENASVEKLKDALQRDPAG---AQELISAFDTNMDRIQQIGVLAIAFSQDIKTKTIV 302

  Fly   306 RSCLASFESLDTTLIPSLQ-------AHGSDLHSDILEQHFNEEVAKFKAALQEIIDSRALVGCC 363
            ||||||.||||..::|:||       ||    |:::|::|||:|:..|:..:.|||||.:|:...
  Fly   303 RSCLASLESLDACIVPALQLPESTSSAH----HAEVLQEHFNQELLIFRNVIHEIIDSCSLINNY 363

  Fly   364 LEILTSGISATEKLFDKQRLEDLVQISLLLVEHFQLEVNRKGLSETQDRLGEEYYQQFIRVLREC 428
            |::|...|...    ||..|:.:||...::|:||:|.||..||||.    |:..::..|.:||||
  Fly   364 LDMLGERIHVQ----DKSHLKLIVQRGGVVVDHFRLPVNYSGLSED----GKRVHKDLILILREC 420

  Fly   429 KAILMCASQVEPQRILKRFKILRTILRKLHGSLGAGKQEEELPIPLAPLLADDTKGVNEDETHFT 493
            :|::.....|:|:||:||.|||.::|.||...:.....|.:
  Fly   421 QAVVNLDVPVDPKRIVKRLKILYSVLAKLRDLICRDNLEPD------------------------ 461

  Fly   494 GYKTARSGSILYDTERRNRVTRRTDNKLPTNTLDIKSDKA--KPHGNVLRRESLRTVMFKRQNIA 556
                   .|:..:.:..:..||..          ::|.::  |.|.:.:::....:|...:.::|
  Fly   462 -------SSVASEAQVPSSATRTF----------VRSSRSFGKRHRSFVKQTGNCSVFGPQDSLA 509

  Fly   557 ESRKLYTSMSNQSTDL---QITDIL 578
            ||       .:..:||   |||:||
  Fly   510 ES-------GHSESDLISFQITEIL 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt	NP_610423.3	Serendipity_A	1..468	CDD:368466	177/493 (36%)
Sry-alpha	NP_524580.1	Serendipity_A	1..530	CDD:368466	195/610 (32%)