Protein Alignment Spt and Ctnna1

DIOPT Version :10

• Sequence 1: NP_610423.3
• Gene: Spt / 35889
• FlyBaseID: FBgn0033348
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001007146.1
• Gene: Ctnna1 / 307505
• RGDID: 1359485
• Length: 908
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 90/494 - (18%)
• Similarity: 197/494 - (39%)
• Gaps: 105/494 - (21%)

  Fly   151 KEVL--PLS---QKLRANID-----LILGQSLGFANVALSQDKRALSALCQKVIRECNAFQEECK 205
            |:::  |||   ::.|.:::     :|.|.:| .|:.:.::|.|.     ::::.||||.::..:
  Rat   289 KQIIVDPLSFSEERFRPSLEERLESIISGAAL-MADSSCTRDDRR-----ERIVAECNAVRQALQ 347

  Fly   206 ESFSANYLSTL--KLRAMTMEQAIYQLEDFINDALLRLVFTCFLD-----FEKFSVDKIRALLRN 263
            :..| .|:...  |.|:..:..||.::.....| |.|.:....:|     |.:.:|..:..:...
  Rat   348 DLLS-EYMGNAGRKERSDALNSAIDKMTKKTRD-LRRQLRKAVMDHVSDSFLETNVPLLVLIEAA 410

  Fly   264 SPDNDDLADEFIADFDVNIDRATQIGIFAISFAPNLKMKTIMRSCLASFESLDTTLIPSLQAHGS 328
            ...|:....|:...|..:.::..::...|.|.:.|.:...::|...:..|:|...:|.:..|..:
  Rat   411 KNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAA 475

  Fly   329 DLHSDILEQH---FNEEVAKFKAALQEIIDSRALVGCCLEILTSGISATEKLFDKQRLEDLVQIS 390
            ...|.:.:::   |.|:..|....|.:.:|....:...|.:..:.|           |||:.:..
  Rat   476 KPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHI-----------LEDVNKCV 529

  Fly   391 LLLVEHFQLEVNRKGLSETQDRLGEEYYQQFIRVLRECKAILMCASQV---EP----QRILKRFK 448
            :.|.|.   :|:  ||..|...:..          |..:.|.:..|::   ||    :::|:..|
  Rat   530 IALQEK---DVD--GLDRTAGAIRG----------RAARVIHVVTSEMDNYEPGVYTEKVLEATK 579

  Fly   449 IL-RTILRKLHGSLGAGKQEEELPIPLAPLLADDTKGVNEDE------THFTGYKTARSGSILYD 506
            :| .|::.:.         .|::...:..|.:|..:.::|:|      ..:.|.:..|...::..
  Rat   580 LLSNTVMPRF---------TEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIR 635

  Fly   507 TERRNRVTRRTDNKLPTNTLDIKSDKA--KPHGNVLRRESLRTVMF-----KRQNIA-------- 556
            |..     ...|:...|...|::|..:  .....::..:|.|.:|.     ::..||
  Rat   636 TPE-----ELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQE 695

  Fly   557 ESRKLYTSMS---NQSTDL-----QITDILDQLTGMSNG 587
            |..||...:|   :...|:     |:..|:.::|..:.|
  Rat   696 EKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRG 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt	NP_610423.3	Serendipity_A	1..468	CDD:368466	64/344 (19%)
Ctnna1	NP_001007146.1	Vinculin	19..869	CDD:460040	90/494 (18%)