Protein Alignment Spt and hmp-1

DIOPT Version :10

• Sequence 1: NP_610423.3
• Gene: Spt / 35889
• FlyBaseID: FBgn0033348
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001122991.1
• Gene: hmp-1 / 179624
• WormBaseID: WBGene00001978
• Length: 930
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 104/570 - (18%)
• Similarity: 192/570 - (33%)
• Gaps: 191/570 - (33%)

  Fly    85 SHQYF-LDRIRWCLKRLMHLYSEESSSEAVAPERSFLKLVDGALDCLAQFTSHSEENTD-TSNCP 147
            ||.|| :|.:|                               :.:.|.|.|....|.|: |...|
 Worm     7 SHAYFNIDEVR-------------------------------SKNVLKQITQLINEVTNITETFP 40

  Fly   148 KTPKEVLPLSQKLRANIDLILGQSLGFANVALSQ------DKRALSALCQKVIRECNAFQEECKE 206
            ..|.:.   ::.|.|.:|..:...|...:.|:|:      |.||:..|.:.:    .|.|:
 Worm    41 LKPGQT---TEGLVATLDAAVANFLQTGSFAISKCPIANSDPRAIDLLHEAL----GAVQD---- 94

  Fly   207 SFSANYLSTLKLRAMTMEQAIYQLEDFINDALLRLVFTCFLDFEKFSVDKIRALLRNSPDN---- 267
                           |.:..|....||:.|:.              |.:| ||:..||..|
 Worm    95 ---------------TGQVMIQTGRDFVRDST--------------STNK-RAIATNSGRNLLTA 129

  Fly   268 ----DDLADEFIADFDVNIDRATQIGIFA---ISFAPNLKMKTIMRSCLASFESLDTTLIPSLQA 325
                ..|||..  |..|.:|:..::...|   |.....:|:..:....::..|.||.|:
 Worm   130 VAKFLILADSI--DVKVIVDKVDEVRETAHQMIEADTKIKVDDLYNLLISQIEELDITV------ 186

  Fly   326 HGSDLHSDILEQHFNEEVAKFKAALQEII-----------------DSRALVGCCLEILTSGISA 373
              .....|:::.:..:::...::||::..                 ::|.......:.:.|.::|
 Worm   187 --RRRAIDLVKPNQRDDLLAARSALRQTAPLLYTSTRTFVRHPEHEEARRNRDYTADEMHSALNA 249

  Fly   374 TEKLFDKQ----------RLEDLVQISLLLVEHFQ--LEVN----RKGLSETQDRLGEEYYQQFI 422
            .|.:.:.|          |:.||:.    .::.||  :|::    |:| ::..|..|
 Worm   250 LESVLNGQQPKVTFSEYGRIGDLIN----EIDTFQNRIEIDPAHYRRG-TDRPDLEG-------- 301

  Fly   423 RVLRECKAILMCASQV---------EPQRILKRFKILRTILRKL--HGSLGAGKQEEELPIPLAP 476
                .|:.|:..::.:         ..|:|:.....||..|::|  ......|::::...|||.
 Worm   302 ----HCERIVSGSASIADAESTRENRKQKIVAECNNLRQALQELLTEYEKSTGRRDDNDDIPLG- 361

  Fly   477 LLADDTKGVNEDETHFTGYKTARSGSILYDTERRNRVTRRTDNKLPTNTLDIKSDKAKPHGNVLR 541
             :|:..|...:...|.                ||..|...:|..|.|.|..|...:|...|:. .
 Worm   362 -IAEVHKRTKDLRRHL----------------RRAIVDHISDAFLDTRTPLILLIEAAKEGHE-E 408

  Fly   542 RESLRTVMFKR--QNIAESRKLYTSMSN--------QSTDLQITDILDQL 581
            ....|:.||:.  ..|....:|...:|:        |.|..|:..:..|:
 Worm   409 NTRYRSKMFQEHANEIVSVARLSCQLSSDVESVSVIQHTAAQLEKLAPQV 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt	NP_610423.3	Serendipity_A	1..468	CDD:368466	78/445 (18%)
hmp-1	NP_001122991.1	Vinculin	15..869	CDD:460040	99/562 (18%)