Protein Alignment Cyp4e2 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_012822016.1
• Gene: cyp26a1 / 548901
• XenbaseID: XB-GENE-855583
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 128/518 - (24%)
• Similarity: 206/518 - (39%)
• Gaps: 117/518 - (22%)

  Fly     9 LALPLLLV---AYL-ELSTFRRRRVLNKFN----GPRGLPLMGNAHQMGKNPSEILDTVFSWWHQ 65
            ||||:||:   |.| |:....|:....: |    |..|||..|...||.....:.|...   ..:
 Frog    14 LALPVLLLLTAAKLWEVYCLSRKDASCR-NPLPPGTMGLPFFGETLQMVLQRRKFLQVK---RRK 74

  Fly    66 YGKDNFVFWIGTYSNVLVTSSKYL-EFILSSQTLITKSDIYQLTHPW-------LGLGLLTSTGS 122
            ||:.......|: ..|.||.::.: :.:|....|::       .| |       ||.|.|::...
 Frog    75 YGRIYKTHLFGS-PTVRVTGAENVRQILLGEHKLVS-------VH-WPASVRTILGAGCLSNLHD 130

  Fly   123 KWHKH-RKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTA 186
            ..||: :|:|..||....|.::..:|.|...:
 Frog   131 SEHKYTKKVIMQAFSREALANYVPLMEEELRR--------------------------------- 162

  Fly   187 MGVSINAMENRSSSIV--QAFKDMCYNINMR--------------------AFHPLKRNELLYRL 229
               |:|......|.::  .|.|.:.:.|.||                    ||..:.||  |:.|
 Frog   163 ---SVNLWLQSDSCVLVYPAIKRLMFRIAMRLLLGCDPQRLGREQEETLLEAFEEMTRN--LFSL 222

  Fly   230 APDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-----G 289
            ..|.| :|...:.|:  ...||..:||        .|..::..|:........|...||     |
 Frog   223 PIDVP-FSGLYRGLR--ARNIIHAQIE--------ENIKEKLQREPDGQCRDALQLLIDHSRRTG 276

  Fly   290 RPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKE---QREVMGNSELGRDAT 351
            .|:|.:.|.|..:..:|.||.||.|..:.....|:.|:|...|:.||   |..:....|..::.:
 Frog   277 EPVNLQALKESATELLFGGHGTTASAATSLTTFLALHKDVLEKVRKELESQGLLSNKPEEKKELS 341

  Fly   352 FQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDP 416
            .:.:.|:||....|||..|:.|.|....|...|.:|::|..:|||..:...:.......::|.|.
 Frog   342 IEVLQQLKYTSCVIKETLRLSPPVAGGFRVALKTFVLNGYQIPKGWNVIYSIADTHGEAELFPDK 406

  Fly   417 HKFRPERFELEKPGP---FEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN--FEVL---PAL 471
            .:|.|:||....||.   |.::||..|.|.|:|::||.:.:|..:.::.||  :|:|   ||:
 Frog   407 DEFNPDRFLTPLPGDSSRFGFIPFGGGVRCCVGKEFAKILLKVFIVELCRNCDWELLNGSPAM 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	107/451 (24%)
cyp26a1	XP_012822016.1	cytochrome_P450	55..485	CDD:477761	113/476 (24%)