Protein Alignment Cyp4e2 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 496
• Identity: 104/496 - (20%)
• Similarity: 191/496 - (38%)
• Gaps: 95/496 - (19%)

  Fly    35 GPRGLPLMG-------NAHQMGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFI 92
            |..|.|..|       ...:...:..|...|||. .|..|:          ..:.|:.::.:..|
Mouse    52 GSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFK-THLLGR----------PVIRVSGAENVRTI 105

  Fly    93 LSSQTLITKSDIYQLTHPWLGL-GLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIK 156
            |..:..:.:|...|..|..||. .||.:.|....:.||::...|..:.|:.|   :........:
Mouse   106 LLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVFSRSSLEQF---VPRLQGALRR 167

  Fly   157 HLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLK 221
            .:::..|........:.|..||..:.....:|:.::  |.|.:.:...|:.:..|
Mouse   168 EVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLD--EARCTELAHTFEQLVEN---------- 220

  Fly   222 RNELLYRLAPDYPAYS------RTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLD 280
                |:.|..|.| :|      |....|.:..:|.:|::::..:    :...||       |.|.
Mouse   221 ----LFSLPLDVP-FSGLRKGIRARDQLYEHLDEAVAEKLQEKQ----TAEPGD-------ALLL 269

  Fly   281 TLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSE 345
            .:.|:...|...:.:||.|.....:|....||.|..:..:.||.:|   ...:.|.|:|:....
Mouse   270 IINSARELGHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQH---PAAITKIQQELSAQG- 330

  Fly   346 LGR-------------------DATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD 391
            |||                   |.:...:.:::|:|..:||..|:.|.|....|...:.:.:||.
Mouse   331 LGRACTCTPRASGSPPDCGCEPDLSLAMLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGY 395

  Fly   392 LVPKGTTLNLGLVMLGYNEKVFKDPHK-FRPERFELE------KPGPFEYVPFSAGPRNCIGQKF 449
            .:|||.::...:........|::.|.: |.||||.:|      ..|.|.|:||..|.|:|:||:.
Mouse   396 QIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQEL 460

  Fly   450 ALLEIKTVVSKIIRN---------FEVLPALDELVSKDGYI 481
            |...::.:..:::|.         |.|:..:..:...||.:
Mouse   461 AQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	94/456 (21%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	101/489 (21%)