Protein Alignment Cyp4e2 and Cyp4a30b

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_006503285.1
• Gene: Cyp4a30b / 435802
• MGIID: 3717145
• Length: 510
• Species: Mus musculus
• Alignment Length: 467
• Identity: 139/467 - (29%)
• Similarity: 234/467 - (50%)
• Gaps: 55/467 - (11%)

  Fly    71 FVFWI-GTYSNVLVTSSKYLEFILS-SQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITP 133
            :|.|: |.::.|::....|::.||. |...:.:|  |....||:|.|||...|.||.:||:|:||
Mouse    84 YVRWLWGNHARVVIYDPDYMKVILGRSDPKVVRS--YSFFAPWIGYGLLLLNGKKWFQHRRMLTP 146

  Fly   134 AFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAM----GVSINAM 194
            |||::||:.:..:|.::....:...:.:...|...:..:....:|::.:...|.    .|.:...
Mouse   147 AFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETMMKCAFSYQGSVQLEDC 211

  Fly   195 ENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHK 259
            .| |.|.::|.:|:.:.|.:|..:...:|..:|.|:.:..::....:.....|..:|..|    |
Mouse   212 RN-SKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRSFYHACQIAHKHTERVIRMR----K 271

  Fly   260 SGAVSTNAGDEFTRKK-MAFLDTLL-SSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYL 322
            :...:....::|.:|| :.|||.|| :.|.||:.|:.:::..|:.|||||||:||.||:|:..|.
Mouse   272 AQLQNEAELEKFRKKKRLDFLDILLFAQTEDGKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYA 336

  Fly   323 LSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYV 387
            |:.|.:.|::..:|.:.::||   |...|...:.||.|..:.||||.|:||.:|...|.......
Mouse   337 LATHPEHQQRCREEVKSILGN---GTSVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVT 398

  Fly   388 I-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG----PFEYVPFSAGPRNCIGQ 447
            . ||..:|||..:.|....|.:|.::..:...|.|.||   .||    ...::|||||.|||||:
Mouse   399 FPDGCSLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRF---APGAPRQTHAFLPFSAGTRNCIGK 460

  Fly   448 KFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTL 512
            :|.:.|:|..|:..:..||:||                          ||.|   .|||.:.:.|
Mouse   461 QFTMNELKVAVALTLLRFELLP--------------------------DPTR---VPILVSKIVL 496

  Fly   513 KSENGLYIRLKE 524
            ||:||:|:..|:
Mouse   497 KSKNGIYLHTKK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	137/461 (30%)
Cyp4a30b	XP_006503285.1	CYP4B-like	70..505	CDD:410771	138/462 (30%)