Protein Alignment Cyp4e2 and Cyp6d4

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 124/563 - (22%)
• Similarity: 226/563 - (40%)
• Gaps: 102/563 - (18%)

  Fly    10 ALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQYGKDNFVFW 74
            :|.||.|..|.|:.|..:|....:. .||.|.    .:....|...||:|   |.|........:
  Fly     3 SLILLAVTLLTLAWFYLKRHYEYWE-RRGFPF----EKHSGIPFGCLDSV---WRQEKSMGLAIY 59

  Fly    75 IGTYSNVLVTSSK-----YLEFILSSQTLITKSDIYQ--LTHPW----------------LGLGL 116
                 :|.|.|.:     ||.|  ....||..:|:.:  |...:                |...:
  Fly    60 -----DVYVKSKERVLGIYLLF--RPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANI 117

  Fly   117 LTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHL--KTVAAGDNIFDFQEQAHYLTL 179
            .:..|..|...|.|::|.|....|:.......:...|.:.||  :....|....|.::......:
  Fly   118 FSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAI 182

  Fly   180 DVICDTAMGVSINAMENRSS------SIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSR 238
            |:|..|..|:.:|:.||..:      |:.:|.........|..|......:.|:|:....|....
  Fly   183 DIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLA 247

  Fly   239 TLKTLQD----------FTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDG--RP 291
            .|:.:::          ...:::...|:...:|.:..|....|:.:|          |.||  :.
  Fly   248 MLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQK----------TPDGHIKT 302

  Fly   292 LNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEIS 356
            ::.:.:..:...|...|.:||.|..:|.:|.|:::.:..::|..|..|.:..:: |: .|:..::
  Fly   303 ISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKND-GK-ITYDSLN 365

  Fly   357 QMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI--DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKF 419
            :|::|||.::|..|.||.:|.:.|...:||.:  ...::||||.:.:.|..:.::.:.|.||..:
  Fly   366 KMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETY 430

  Fly   420 RPERF--ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYIS 482
            .||||  |.....|..::||..|||.||.|:...:..|..:.||::||.|     |::|:.....
  Fly   431 DPERFSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNV-----EVMSRSEIEF 490

  Fly   483 TTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKER 525
            ...|                       :.|..::|:.:||.:|
  Fly   491 ENSG-----------------------IALIPKHGVRVRLSKR 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	104/498 (21%)
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	101/479 (21%)