Protein Alignment Cyp4e2 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_956773.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 444
• Species: Danio rerio
• Alignment Length: 437
• Identity: 121/437 - (27%)
• Similarity: 214/437 - (48%)
• Gaps: 42/437 - (9%)

  Fly    48 MGKNPSEILDTVFSWWHQYGKDNFVFWIGT--YSNVLVTSSKYLEFILSSQTLITKSDIYQ---- 106
            |..:.|.|.|....|..:||.   |:.|.:  |..::|...:..:.||.|........:|:
Zfish     1 MYADDSLIHDLFLQWAEKYGP---VYRINSLHYIAIVVHCPEATKTILMSPKYTKDPFVYRRLFN 62

  Fly   107 -LTHPWLGLGLLTSTGSK-WHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFD 169
             ....:||.||:|:.... |::.|:::.|||..:.|:......:|.|.:.:..|:.:|.......
Zfish    63 LFGKRFLGYGLITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPAV 127

  Fly   170 FQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYN---INMRAFHPLKRNELLYRLAP 231
            ..:..:.:||||||..|.||.:|.:..:.|....|. ::|.|   :::|        :..:||
Zfish   128 MHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQNAV-ELCLNGMTVDLR--------DPFFRL-- 181

  Fly   232 DYPAYSRTLKTLQDFTNEIIAKRIE---AHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLN 293
             :|...:.:|.::| ..|::.|..|   .::..||..  |::..:.   .|..:|.|..:....|
Zfish   182 -FPKNWKLIKQIRD-AAELLRKTGEKWIQNRKTAVKN--GEDVPKD---ILTQILKSAEEENVNN 239

  Fly   294 SKELYEEVS---TFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEI 355
            :.:|.:.:.   ||...|.:||.:.:|||:..|.|:.:..::...|..||:|..   |:.:.:::
Zfish   240 TDDLEQMLDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTK---REISNEDL 301

  Fly   356 SQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFR 420
            .:..||...:||..|:||:.|...|:..:|.:|||..:|.|.::.....:....||.||||.||.
Zfish   302 GKFTYLSQVLKETLRLYPTAPGTNRWLHEDMIIDGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFD 366

  Fly   421 PERFELEKPGPFE-YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
            ||||::..|.|:. |.||:.|||.|:||.|:.:|.|.|::|:::.||
Zfish   367 PERFDVNAPKPYYCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQRFE 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	114/417 (27%)
cyp46a1.4	NP_956773.1	CYP46A1-like	9..438	CDD:410706	118/429 (28%)