Protein Alignment Cyp4e2 and Cyp6a20

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 567
• Identity: 130/567 - (22%)
• Similarity: 233/567 - (41%)
• Gaps: 124/567 - (21%)

  Fly    11 LPLLLVAYLELSTFRRRRVLNKFN--GPRGLPLMGNAHQMGK----NPSEILDTVFSWWHQYGKD 69
            :.:::|..:.:.||....|...||  ..||:|     |...|    |.||::.||      :..|
  Fly     1 MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIP-----HDEPKIPYGNTSELMKTV------HFAD 54

  Fly    70 NFVFWIGTYSNVL-VTSSKYLEFILSSQTLITKSDI----------YQLTH-----------PWL 112
            .|.   .||:.:. .|...::.|.:..:.::..:||          :...|           | |
  Fly    55 IFK---RTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDP-L 115

  Fly   113 GLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYL 177
            ...|:...|.||...|:.:||.|....::.....:.....:.|:.....|:.|:  |..|..:.:
  Fly   116 SANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADS--DSMEITNVV 178

  Fly   178 ---TLDVICDTAMGVSINAMENRSSSIVQ----AFKDMCYNINMRAFHPLKRNELLYRLAPDYPA 235
               |.|||...|.|:..:::.:..:..||    |..:..:..:|         :||...||:..|
  Fly   179 ARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSM---------DLLLFGAPELAA 234

  Fly   236 YSR---TLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTI--------DG 289
            ..|   |::.::||...||...::..    |..|.      |:..|:|.|:...:        :|
  Fly   235 KLRMKATVQEVEDFYMNIIRDTVDYR----VKNNV------KRHDFVDMLIEMKLKFDNGDKENG 289

  Fly   290 RPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVM--GNSELGRDATF 352
            ...|  |:..:...|...|.:|:::.:.||:|.|:.|||.|.||..|...|:  .|.:|..|:
  Fly   290 LTFN--EIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDS-- 350

  Fly   353 QEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDL--VPKGTTLNLGLVMLGYNEKVFKD 415
              :.:|.||:..|.|..|..|.|..:.|...:.|......  :.|||.:.:..:.:.::.:.:.:
  Fly   351 --MREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPE 413

  Fly   416 PHKFRPERF---ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN--FEVLPALDELV 475
            |.||.||||   ::::.....::||..|||||||.:|..:::...::.:|.|  ||..|.
  Fly   414 PEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPT----- 473

  Fly   476 SKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRL 522
                  .|.:           |..::.|..|     |.|:.|:::::
  Fly   474 ------KTVV-----------PLEYRTDDFL-----LSSKGGIHLKV 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	114/500 (23%)
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	110/482 (23%)