Protein Alignment Cyp4e2 and Cyp6a9

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 127/570 - (22%)
• Similarity: 226/570 - (39%)
• Gaps: 120/570 - (21%)

  Fly     4 VLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLP--LMGNAHQMGKNPSEILDTVFSWWHQY 66
            |..:.||:.::||.||.|...|........:.|...|  |||:.  .|...|.....:  |...|
  Fly     3 VYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSL--TGVQTSRSFSAI--WMDYY 63

  Fly    67 GKDNFV------FWIGTYSNVLVTSSKYLEFILSSQ-TLITKSDIYQLTH--PWLGLGLLTSTGS 122
            .|....      :|. ....:||......:.||..: ...|....|..|.  |..| .|....|.
  Fly    64 NKFRGTGPFAGFYWF-QRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG-QLFLLDGQ 126

  Fly   123 KWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAM 187
            ||...|..::..|....::.....:.:...:||:..........|.:.::.....|.|||...|.
  Fly   127 KWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAF 191

  Fly   188 GVSINAM----------------ENRSSSI----VQAFKDMCYNINMRAFHPLKRNELLYRLAPD 232
            |:..:::                |.|...|    :.:|:::...::|:.
  Fly   192 GIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKI---------------- 240

  Fly   233 YPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKEL 297
                  ||:..:.|...|:.:.:...:...:..|          .|:|.|:.  :...||...|.
  Fly   241 ------TLEEAEHFFLRIVRETVAFREKNNIRRN----------DFMDQLID--LKNSPLTKSES 287

  Fly   298 YEEVS---------TFMF--EGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMG--NSELGRD 349
            .|.|:         .|:|  .|.:|:::.:.||:|.|::|||.|.::.||.:||:|  |.|:
  Fly   288 GESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEI--- 349

  Fly   350 ATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD---LVPKGTTLNLGLVMLGYNEK 411
             |::.:..|.|||..|.|..|:|..:|.:.|...:||.:.|.   ::.||..:.:....:..:||
  Fly   350 -TYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEK 413

  Fly   412 VFKDPHKFRPERFELEK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDE 473
            ::.:|:.|.|:.|..|:   ....|::||..|||||||.:|..::.::.::.:|..|:.  ::.|
  Fly   414 LYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKF--SVCE 476

  Fly   474 LVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLK 523
                    .|||  |....||              ...:.||.|::::::
  Fly   477 --------QTTI--PIVYSKK--------------TFLISSETGIFLKVE 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	109/499 (22%)
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	108/495 (22%)