Protein Alignment Cyp4e2 and Cyp4ac3

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 178/528 - (33%)
• Similarity: 283/528 - (53%)
• Gaps: 76/528 - (14%)

  Fly     1 MWFVLY--------IFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQM-GK----NP 52
            ||..|.        ::|.|..|...|..||..:|.|..:      |.||......: ||    |.
  Fly     1 MWIALLGSSLLIGALWLLLRQLNKTYFILSLCKRVRTAD------GSPLESKVFVVPGKTRFGNN 59

  Fly    53 SEILD----TVFSW--------------WHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLI 99
            .::|:    .:||:              |      ||:| ...|:   :..::..|.|..|..:.
  Fly    60 LDLLNLTPANIFSYIRESTAKANGQNYIW------NFLF-APEYN---IVRAEDAEEIFQSTKIT 114

  Fly   100 TKSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAG 164
            ||:..|:|..|:||.|||.|...|||..||.:||||||||||.|..:..|.|.||||.|
  Fly   115 TKNMSYELIRPFLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKIL------ 173

  Fly   165 DNIFDFQEQAHYL----TLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNEL 225
            |....|:.:.:.:    ||:.||:||:||.::.| :..:...:|..|.....|.|..:||.....
  Fly   174 DKNVGFELELNQIIPQFTLNNICETALGVKLDDM-SEGNEYRKAIHDFEIVFNQRMCNPLMFFNW 237

  Fly   226 LYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKS---GAVSTNAGDEFTRK-KMAFLDTLLSST 286
            .:.|..||..|||.|:|:..|::.||.::.:..|.   |.|     |||.:| :.|.|||||::.
  Fly   238 YFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQV-----DEFGKKQRYAMLDTLLAAE 297

  Fly   287 IDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDAT 351
            .:|: ::.:.:.:||:||||.|:|||::.:.|.:.||:.|.|.|.:.::|.:::  ..::...:.
  Fly   298 AEGK-IDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDL--PEDIDEVSM 359

  Fly   352 FQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDP 416
            || .:::.:|:..|||:.|::||.|.|||...::.|::|.::||...:::.:..:..:.:.|..|
  Fly   360 FQ-FNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKP 423

  Fly   417 HKFRPERFELEKP---GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPA--LDELVS 476
            ::|.||||..|..   .||.:|||||||||||||||.:||||.:::.:||||::|||  |::|..
  Fly   424 NQFLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDLTF 488

  Fly   477 KDGYISTT 484
            ::|.:..|
  Fly   489 ENGIVLRT 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	157/430 (37%)
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	158/436 (36%)