Protein Alignment Cyp4e2 and Cyp28d2

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 126/586 - (21%)
• Similarity: 240/586 - (40%)
• Gaps: 159/586 - (27%)

  Fly     6 YIFLALPLLLVAYLELS---TFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQY- 66
            ::.|.|.||::.|:.|:   .:.|:|.:.  ..|. .|.:|:...:......|...:...:.:|
  Fly     7 FLVLVLTLLVLVYVFLTWNFNYWRKRGIK--TAPT-WPFVGSFPSIFTRKRNIAYDIDDIYEKYK 68

  Fly    67 GKDNFVFWIGTYS----NVLVTSSKYLEFILSS----------QTLITKSDIYQLTHPWLGLGLL 117
            ..||.|   |.::    .:||...:|:..|.::          :..:.|.     |...||....
  Fly    69 DTDNMV---GVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKK-----TDMILGNNPF 125

  Fly   118 TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLK---TVAAGDNIFDFQEQAHYLTL 179
            ..||.:|.:.|..|.||...|.::..:.|......||:::::   .:|..:.: |..:.:...|.
  Fly   126 VLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGL-DAMDLSLCYTT 189

  Fly   180 DVICDTAMGVSINAMENRSSSIVQ--------AFKDMCYNI------NMRAFHPL----KRNELL 226
            :|:.|..:|||..:..:..:.:::        :|:.:.|::      .:|.|:.:    |..|:.
  Fly   190 EVVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTSFEFIFYSVVTNLWQKVRKFYSVPFFNKETEVF 254

  Fly   227 Y--------RLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLL 283
            :        .|..:.|...|     .||.|.::                  :...||....|.:|
  Fly   255 FLDIIRRCITLRLEKPEQQR-----DDFLNYML------------------QLQEKKGLHTDNIL 296

  Fly   284 SSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGR 348
            .:|:               ||:.:|.:||...::..:.:|.|:.:||.|:.||    :|:::|
  Fly   297 INTM---------------TFILDGFETTALVLAHIMLMLGRNPEEQDKVRKE----IGSADL-- 340

  Fly   349 DATFQEISQMKYLDLFIKEAQRVY-PSV--------PFIGRFTEKD----YVIDGDLVPKGTTLN 400
              ||.::|::.:||..|.|..|:: |.|        ||  .|..|:    ::..||:|      .
  Fly   341 --TFDQMSELPHLDACIYETLRLFSPQVAARKLVTEPF--EFANKNGRTVHLKPGDVV------T 395

  Fly   401 LGLVMLGYNEKVFKDPHKFRPERFELEKPGPFE-------YVPFSAGPRNCIGQKFALLEIKTVV 458
            :.:..|.::.:.::||..|:||||.....|..:       |:.|..|||:|.|.:|||.::|..:
  Fly   396 IPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAAL 460

  Fly   459 SKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLK 523
            .:|:||||:  .::.....|..|..|.                      .:.|||  .|:|:..|
  Fly   461 VEILRNFEI--KVNPKTRSDNQIDDTF----------------------FMATLK--GGIYLDFK 499

  Fly   524 E 524
            :
  Fly   500 D 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	111/514 (22%)
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	109/509 (21%)