Protein Alignment Cyp4e2 and Cyp18a1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 126/553 - (22%)
• Similarity: 211/553 - (38%)
• Gaps: 106/553 - (19%)

  Fly     4 VLYIFLALPLLLVAYLELSTFRRRRVLNKF-NGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQYG 67
            :|.:||.| |.||..|:. ..|..|.|.|. .||.|||::|....||   ||..........|||
  Fly    26 LLMVFLGL-LALVTLLQW-LVRNYRELRKLPPGPWGLPVIGYLLFMG---SEKHTRFMELAKQYG 85

  Fly    68 KDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWL----GLGLLTSTGSKWHKHR 128
             ..|...:|:...|:::..|.:......:....:.|.     |::    |.|::.|||..|...|
  Fly    86 -SLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDT-----PFMQTLNGYGIINSTGKLWKDQR 144

  Fly   129 KMI---------------TPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLT 178
            :.:               .......|:.:.||        ||.||.  |:.....|.........
  Fly   145 RFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHE--------FIGHLH--ASDGQPVDMSPVISVAV 199

  Fly   179 LDVICDTAMGVSINAMENRSSSIVQAFKDMCYNI--NMRAFHPLKRNELLYRLAPDYPAYSRTLK 241
            .:|||...|....:..:.:       |:...:.|  .||.|..:.        ..||....:...
  Fly   200 SNVICSLMMSTRFSIDDPK-------FRRFNFLIEEGMRLFGEIH--------TVDYIPTMQCFP 249

  Fly   242 TLQDFTNEIIAKR----------IEAHKSGAVSTNAGD-------EFTRKKMAFLDTLLSSTIDG 289
            ::....|:|...|          |:.||......|..|       |..:.|....|..|   .||
  Fly   250 SISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAEL---FDG 311

  Fly   290 RPLNSKELYEEVSTFMFE-GHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQ 353
            :  |.:|...:|...:|. |.:|..:.:.:....:.|:..|.|::..|..:|:|...|   .|.:
  Fly   312 K--NHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRL---PTIE 371

  Fly   354 EISQMKYLDLFIKEAQRVYPSVPFIGRFT-EKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPH 417
            ::..:...:..|.|:.|....||.....: .:|..::|..:|.|:.:...:..:..:..:::.|.
  Fly   372 DLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPE 436

  Fly   418 KFRPERF-----ELEKPGPFEY-VPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV-LPALDELV 475
            :|||.||     ::.||   || :||..|.|.|:|...|.:|:....:..:..|:: ||....|.
  Fly   437 EFRPSRFIDTEGKVRKP---EYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLP 498

  Fly   476 SKDGYISTTIGLPDAER---KKR-------DPY 498
            |..|.:..|| .|::.:   |:|       ||:
  Fly   499 SLKGNVGATI-TPESFKVCLKRRPLGPTAADPH 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	101/488 (21%)
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	98/472 (21%)