Protein Alignment Cyp4e2 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_217935.3
• Gene: Cyp26c1 / 308190
• RGDID: 1308843
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 109/504 - (21%)
• Similarity: 196/504 - (38%)
• Gaps: 97/504 - (19%)

  Fly    35 GPRGLPLMG-------NAHQMGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFI 92
            |..|.|..|       ...:...:..|...|||. .|..|:          ..:.|:.::.:..|
  Rat    52 GSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFK-THLLGR----------PVIRVSGAENVRTI 105

  Fly    93 LSSQTLITKSDIYQLTHPWLGL-GLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIK 156
            |..:..:.:|...|..|..||. .||.:.|.:..:.||::...|....|:.|...:.|   ...:
  Rat   106 LLGEHRLVRSQWPQSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPALEQFVPRLQE---ALRR 167

  Fly   157 HLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLK 221
            .:::..|........:.|..||..:.....:|:.::  |.|.:.:.|.|:.:..|
  Rat   168 EVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLD--EARCTELAQTFERLVEN---------- 220

  Fly   222 RNELLYRLAPDYPAYS------RTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLD 280
                |:.|..|.| :|      |....|....:|:||:::.            :|.|.:....|.
  Rat   221 ----LFSLPLDVP-FSGLRKGIRARDQLYQHLDEVIAEKLR------------EELTAEPGDALH 268

  Fly   281 TLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNS 344
            .:::|..: ||.|:.:||.|.....:|....||.|..:..:.||.:|   ...:.|.|:|:....
  Rat   269 LIINSARELGRELSVQELKELAVELLFAAFFTTASASTSLILLLLQH---PAAIAKIQQELSAQG 330

  Fly   345 ELGR-------------------DATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDG 390
             ||.                   |.:...:.:::|:|..:||..|:.|.|....|...:.:.:||
  Rat   331 -LGSPCSCAPRASGSRPDCSCEPDLSLAVLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDG 394

  Fly   391 DLVPKGTTLNLGLVMLGYNEKVFKDPHK-FRPERFELEKP------GPFEYVPFSAGPRNCIGQK 448
            ..:|||.::...:........|::.|.: |.||||.:|..      |.|.|:||..|.|:|:||:
  Rat   395 YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDARGSGGRFHYIPFGGGARSCLGQE 459

  Fly   449 FALLEIKTVVSKIIRN---------FEVLPALDELVSKDGYISTTIGLP 488
            .|...::.:..:::|.         |.|:..:..:...||.:.....||
  Rat   460 LAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLLLLFHPLP 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	99/464 (21%)
Cyp26c1	XP_217935.3	cytochrome_P450	59..504	CDD:477761	104/491 (21%)