Protein Alignment Cyp4e2 and erg11

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02C
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 539
• Identity: 107/539 - (19%)
• Similarity: 202/539 - (37%)
• Gaps: 123/539 - (22%)

  Fly     2 WFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQ- 65
            |:|.||.          .:|::...:|....|:   .:|.:|:|...|.:|       :.::.:
pombe    16 WYVGYII----------NQLTSRNSKRPPIVFH---WIPFVGSAVAYGMDP-------YVFFREC 60

  Fly    66 ---YGKDNFVF---------WIGTYSNVLVTSSKYLEFILSSQTLITKSDIY-QLTHPWLGLGLL 117
               || |.|.|         ::|...|..:.:.|..:        :...:.| .||.|..|..::
pombe    61 RAKYG-DVFTFVCMGRKMTAFLGVQGNDFLFNGKLAD--------LNAEEAYSHLTTPVFGKDVV 116

  Fly   118 TSTGSK-WHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAG-DNIFDFQEQAHYLTLD 180
            ....:. :.:|:|.|.....|:..:.:..::......|:........| :.:.|..:....:|:.
pombe   117 YDIPNHVFMEHKKFIKSGLGFSQFRSYVPLILNEMDAFLSTSPDFGPGKEGVADLLKTMPVMTIY 181

  Fly   181 VICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFH---------PLKRNELLYRLAPDYPAY 236
            ....|..|..:.      ......|.|:.:::: :.|.         ||.||.          ..
pombe   182 TASRTLQGAEVR------KGFDAGFADLYHDLD-QGFSPVNFVFPWLPLPRNR----------RR 229

  Fly   237 SRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTI-DGRPLNSKELYEE 300
            .|..|.:|....:||..|..:      :.|.|.:       .:.||:|... |||||...|:...
pombe   230 DRAHKIMQKTYLKIIKDRRSS------TENPGTD-------MIWTLMSCKYRDGRPLKEHEIAGM 281

  Fly   301 VSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMG-NSELGRDATFQEISQMKYLDLF 364
            :...:..|..|:.:.:.:.:.||....:....|::||:.|:| |.||    .|.:...|..|:..
pombe   282 MIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENLEL----KFDQYKDMPLLNYV 342

  Fly   365 IKEAQRVYPSVPFIGRFTEKDYVIDGD--LVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFE-- 425
            |:|..|::|.:....|..::|..:.|.  ::|....|.....:....|:.|.....|.|:|:.
pombe   343 IQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGLTATEEEYFTHATDFDPKRWNDR 407

  Fly   426 ----------------LEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE-----VLP 469
                            :.|.....|:||.||...|||::||.:.:.|::||.:.::.     .:|
pombe   408 VNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMHLSTIISKFVHDYTWTLIGKVP 472

  Fly   470 ALDELVSKDGYISTTIGLP 488
            .:|        .|:.:.||
pombe   473 NVD--------YSSMVALP 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	93/469 (20%)
erg11	NP_592990.1	CYP51-like	60..492	CDD:410668	95/475 (20%)