Protein Alignment Cyp4e2 and cyp-29A2

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_505847.1
• Gene: cyp-29A2 / 179550
• WormBaseID: WBGene00011830
• Length: 503
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 187/541 - (34%)
• Similarity: 277/541 - (51%)
• Gaps: 61/541 - (11%)

  Fly     7 IFLALPL-LLVAYL-----ELSTFRRR-RVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWW- 63
            ||:.:.: :::|||     .|..::|. :..:|..||...|:.||...:....:|.|.:||..|
 Worm     3 IFIPISIAIILAYLATWIPTLLKYKRHWQYGSKLPGPPAHPIFGNLGPIVGKKTEDLPSVFINWA 67

  Fly    64 -HQYGKDNFVFWIGTYSNVLV--TSSKYLEFILSSQTLITKSDIYQLTHPWLGLG-LLTSTGSKW 124
             .|..:.:.|..:.....|..  .:.|....|:.|.|...|.|.|:...||||.| ||...|.:|
 Worm    68 AEQRDQGHSVMRVMILGKVYAWPLNGKAAAAIIDSTTETNKGDDYRFFDPWLGGGLLLEGYGERW 132

  Fly   125 HKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGV 189
            ..||||:||||||..|..:.||.|..|...|..|...:|.....|.........||:|.:||||:
 Worm   133 KSHRKMLTPAFHFAKLGGYFEVFNNESKILIDLLSDFSASGETVDIFPYVKRCALDIISETAMGI 197

  Fly   190 SINAMENRSSSIVQAFKDMCYN-IN-MRAFHPLKRNELLYRLAPDYPA-YSRTLKTLQDFTNEII 251
            .|:|..|.....|||.:.  || |. :.:|:|..:|:.:: .|..|.| |...|.||:..|.::|
 Worm   198 KIDAQINHDHKYVQAVEG--YNKIGVLVSFNPHLKNQFIF-WATGYKAQYDDYLSTLKSMTEKVI 259

  Fly   252 AKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGV 316
            .:|..||.||.|.    .|.:::.|.|||.:||.. :...|.|:::.:||.||||.|||||||..
 Worm   260 KERRAAHDSGEVE----KETSKRMMNFLDLMLSME-ESNQLTSEDIRQEVDTFMFAGHDTTTSST 319

  Fly   317 SFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRF 381
            |:|.:.|:.:.:.|.|::||..||.|: :...|.|.:.::.:.|||:.:||::|:...||.:.|.
 Worm   320 SWACWNLAHNPNVQEKVYKEMIEVFGD-DPNTDITLENVNNLNYLDIVLKESKRIIAPVPALQRK 383

  Fly   382 TEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELEKPGPFEYVPFSAGPRN 443
            ...|..|||.:||.|..:.:..::|..|..|||:|.:|.|:||   |:.|..|::::||.|||||
 Worm   384 LTNDLEIDGYIVPAGGNVTISPMVLHSNHHVFKNPTEFNPDRFLPDEVSKRHPYDFMPFLAGPRN 448

  Fly   444 CIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYD---PI 505
            |||||||.|..|.::|.|:|||::.|.|                             ||:   |.
 Worm   449 CIGQKFAQLNEKVMISHIVRNFKIEPTL-----------------------------KYNDTKPC 484

  Fly   506 LSAVLTLKSENGLYIRLKERH 526
            |..|  .|..||:.:||..|:
 Worm   485 LEVV--TKPSNGIPVRLIRRN 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	165/463 (36%)
cyp-29A2	NP_505847.1	CYP4	75..497	CDD:410721	165/461 (36%)