Protein Alignment Cyp4e2 and LOC11175708

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_003435958.1
• Gene: LOC11175708 / 11175708
• VectorBaseID: AGAMI1_006592
• Length: 507
• Species: Anopheles gambiae
• Alignment Length: 544
• Identity: 174/544 - (31%)
• Similarity: 285/544 - (52%)
• Gaps: 62/544 - (11%)

  Fly     4 VLYIFLALPLLLVA--YLELSTFRRR-------RVLNKFNGPRGLPLMGNAHQ-MGKNPSEILDT 58
            ||.:||...:||::  |:.|...|.|       :.|..|.....:||:|:||. :...|...|.|
Mosquito     5 VLLLFLLATVLLLSALYIALKVVRNRNRAVALLKQLPNFRALPSVPLLGSAHLFLDTTPDGTLRT 69

  Fly    59 VFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSK 123
            :.....:||::..:..:|....:|....:.:|.:|.::|:: ||:.|:...||:||..:..:|.:
Mosquito    70 IVDCHQRYGRNLLLQELGNEFKLLTCDPRVIEQVLQAKTIV-KSNFYRFLLPWIGLSSVVVSGHR 133

  Fly   124 WHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMG 188
            ||..||:|.|.|::.:||.|...|:..:...:..|...|.|..| |..|....:.:|:||:||||
Mosquito   134 WHNRRKVINPGFNYRMLQGFLPTMDAQAAVLVAKLAPHAGGPAI-DVDEPLRCMAMDIICETAMG 197

  Fly   189 VSINAMENRSSSIVQAFKDMCYN----INMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNE 249
            |.:....|.:   |..||| |..    |..|.|:||...:|:|.........:.|::.|..||..
Mosquito   198 VRLGCQSNPA---VPFFKD-CEELLDLIYKRIFNPLLTYDLVYACTRAGRRANATIRALHQFTRS 258

  Fly   250 IIAKRIEAHKSGAVSTN----AGDEFTRK--KMAFLDTLLSSTIDG-RPLNSKELYEEVSTFMFE 307
            :|.:|::  :..||..|    |.:|...:  :..|||.||.:.:.| :.|:..::..||:||||.
Mosquito   259 VIRERVK--QMQAVLPNSQQPAPEESQEQQHRSTFLDLLLQTRLAGDKLLSDDDIRGEVNTFMFA 321

  Fly   308 GHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVY 372
            ||:|.||.:||.:|.|||:.|.|::|: |:...|..:.:   .|:..:.::||.:|.|:|..|:.
Mosquito   322 GHETVTSCLSFTLYYLSRYPDVQQRLY-EEIATMAKAPV---LTYGTLMELKYTELVIRETLRLN 382

  Fly   373 PSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGPFEYVPF 437
            ||||.|||....|..|||..:|.||.:.|.:.::..:.:.:.|..:|||||| |::|.|:.|:||
Mosquito   383 PSVPMIGRMAAGDMEIDGVTIPTGTEVMLNIYVMQNDPQYYPDADQFRPERF-LQEPPPYSYLPF 446

  Fly   438 SAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKY 502
            |.|.|:||||:||:||:|||:.:::..|..:|..:|...:
Mosquito   447 STGVRSCIGQRFAMLEMKTVLVRLLSRFRFVPCGEENALQ------------------------- 486

  Fly   503 DPILSAVLTLKSENGLYIRLKERH 526
               :.|.||||..:|.:::|.:||
Mosquito   487 ---VKANLTLKPYHGAFVKLVDRH 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	149/462 (32%)
LOC11175708	XP_003435958.1	CYP4	86..498	CDD:410721	148/452 (33%)