Protein Alignment Cyp4e2 and cyp4b1.5

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_031756807.1
• Gene: cyp4b1.5 / 100488227
• XenbaseID: XB-GENE-5810927
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 164/538 - (30%)
• Similarity: 271/538 - (50%)
• Gaps: 65/538 - (12%)

  Fly     5 LYIFLA-LPLLLVAYLELSTFRRRR----VLNKFNGPRGLPLMGNAH---QMGKNPSEILDTVFS 61
            ||.:.| |.||||.|.....:.:||    .|:.|.||:...|.||||   |:||.    ||.:..
 Frog    14 LYSWAASLCLLLVLYKATQLYLKRRFLVAALSPFPGPKSHWLYGNAHEFFQVGKE----LDLILR 74

  Fly    62 W--WHQYGKDNFVFWIGTYSNVL-VTSSKYLEFILSSQTLITKSD-IYQLTHPWLGLGLLTSTGS 122
            |  .:.||..   .|:|.:...| ||...|.:.||..|.  .|.| .|:...||:|.|||..:|.
 Frog    75 WAQVYPYGVS---MWLGNFHAALFVTHPDYAKAILGRQE--PKDDTAYKYLVPWIGKGLLVLSGP 134

  Fly   123 KWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAM 187
            ||.:||:::||.||:::|:.:..:|::.:...:.....:...:...:.......:|||.|...|.
 Frog   135 KWFQHRRLLTPGFHYDVLKQYVSLMSDCTRVMLDKWDKLMPNEKSIELFHHVSLMTLDTIMKCAF 199

  Fly   188 GVSINAMENRSSSIVQAFKDMCYNINMR-AFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEII 251
            ..:.:...||.:..::|..::.|.:..| :|.|. .|::::.|:|....:.:.|......|:::|
 Frog   200 SYNSSCQNNRDNEYIKAVYELSYLVYERSSFFPY-HNDVIFSLSPLGFRFRKALSIAHQHTDKVI 263

  Fly   252 AKRIEAHKSGAVSTNAGDEFTRKK-MAFLDTLL-SSTIDGRPLNSKELYEEVSTFMFEGHDTTTS 314
            ..|    |...::....|:.::|: :.|||.|| :...:|:.|:.::|..||.||||.|||||.|
 Frog   264 KHR----KESLINETELDKISQKRHLDFLDILLFAKDENGKGLSDEDLRAEVDTFMFAGHDTTAS 324

  Fly   315 GVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIG 379
            |:|:.:|.::::.:.|:|..:|..|::|:.|   ...:.::.|:.|....|||:.|:||.||.||
 Frog   325 GISWILYCIAKYPEHQQKCREEITELLGDRE---TMEWGDLGQIPYTTSCIKESLRLYPPVPIIG 386

  Fly   380 RFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG---PFEYVPFSAG 440
            |...|.... ||..:|:||.:...:..:..:..|:|||..|.|.||..|...   |..::|||||
 Frog   387 RRLSKSITFSDGRSLPEGTEVITSIYAINRSPSVWKDPEVFDPSRFSPENSDSRHPHAFIPFSAG 451

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPI 505
            |||||||.||:.|:|.||:..::.:|:.|..|....|         :|.
 Frog   452 PRNCIGQNFAMNEMKVVVALTLQRYELFPDPDNKPQK---------VPQ---------------- 491

  Fly   506 LSAVLTLKSENGLYIRLK 523
                :.|:|.||:.::::
 Frog   492 ----IVLRSLNGINVKIR 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	136/460 (30%)
cyp4b1.5	XP_031756807.1	CYP4B-like	69..503	CDD:410771	141/475 (30%)