Protein Alignment Cyp4e2 and cyp4v2

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_002934446.1
• Gene: cyp4v2 / 100485929
• XenbaseID: XB-GENE-22069503
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 189/540 - (35%)
• Similarity: 283/540 - (52%)
• Gaps: 50/540 - (9%)

  Fly     5 LYIFLALPLLLVAYLELSTF-------RRRRVLNKFNGP-RGLPLMGNAHQMGKNPSEILDTVFS 61
            |.:::|..::|:..|.||..       |:.:::....|| ...|::|:|..:..|..:....:..
 Frog     9 LLVWVAAAVVLLTLLALSILPALQDYVRKWKLMKPIPGPGPNYPIVGDALFLKPNGGDFFLQMCE 73

  Fly    62 WWHQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWH 125
            :...:..:..: .|||....::|..:..:|.|||:...:.|:..|:..|||||.|||||||.||.
 Frog    74 FTESFRSEPLIKIWIGPIPFIIVYHADTVEPILSTSKHMDKAYSYKFLHPWLGKGLLTSTGEKWR 138

  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190
            ..||||||.|||.||.:|.|||||.|...::.|:....|::...|.: .....||:|.:||||..
 Frog   139 SRRKMITPTFHFAILSEFLEVMNEQSKILVEKLQKHVDGESFNCFMD-VTLCALDIISETAMGRK 202

  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRI 255
            |.|..||.|..|.|...|...|..|...|....:..|....|...:.:.||.|..||::.|.:|.
 Frog   203 IQAQSNRDSEYVHAIYKMSDIIQRRQKMPWLWLDFFYAYLKDGKEHDKNLKILHAFTDKAILERA 267

  Fly   256 E------AHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTT 313
            |      ..|.....::...:..:|:.||||.||.:|.| |..::..::.|||.||||||||||.
 Frog   268 EELKKMGEQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTTA 332

  Fly   314 SGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFI 378
            :.::::::||..|.:.||::.||..||.|.|:  |..|..::.:::||:..||||.|:||||||.
 Frog   333 AALNWSLFLLGSHPEAQRQVHKELDEVFGKSD--RPVTMDDLKKLRYLEAVIKEALRIYPSVPFF 395

  Fly   379 GRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKP---GPFEYVPFSAG 440
            .|...:|..|.|..||||..:.:....|..:.:.|.:|.:||||||..|..   .|:.|:|||||
 Frog   396 ARTVTEDCSIRGFHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYIPFSAG 460

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPI 505
            .||||||:|||:|.|.|:|.|:||:.|                     :|.:|:.       |..
 Frog   461 LRNCIGQRFALMEEKVVLSSILRNYWV---------------------EASQKRE-------DLC 497

  Fly   506 LSAVLTLKSENGLYIRLKER 525
            |...|.|:.::|::|:||.|
 Frog   498 LLGDLILRPQDGMWIKLKNR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	172/462 (37%)
cyp4v2	XP_002934446.1	CYP4V	70..512	CDD:410773	172/472 (36%)