Protein Alignment Cyp4e2 and cyp4f3

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001083010.1
• Gene: cyp4f3 / 100037390
• ZFINID: ZDB-GENE-070410-108
• Length: 511
• Species: Danio rerio
• Alignment Length: 559
• Identity: 159/559 - (28%)
• Similarity: 252/559 - (45%)
• Gaps: 87/559 - (15%)

  Fly     1 MWFVLYIFLALPLLLVAYLELSTFR---RRRVLNKFNGPRGLPL----MGNAHQMGKNPSEILDT 58
            |.|.|.:...|.|.:.|.|.....|   .||.|..||.|   ||    ||:...||.| .|.|..
Zfish     1 MLFGLSVTGILALSVAALLCALVTRIIINRRALRCFNQP---PLRNWIMGHMGLMGHN-EEGLQR 61

  Fly    59 VFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSD--IYQLTHPWLGLGLLTSTG 121
            |.....:||.....|....|:.|.:....|:..:|::...||..|  .|....||||..||..:|
Zfish    62 VDDLVCKYGHSCSWFLGPFYNMVRLFHPDYIRSLLTASASITLKDRIFYGFMKPWLGNCLLLQSG 126

  Fly   122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKH---LKTVAAGDNIFDFQEQAHYLTLDVI- 182
            .:|.:||:::||||||:||:.:..:.|:::.  |.|   .:.:|.|::..|..||...||||.:
Zfish   127 QEWSRHRRLLTPAFHFDILKKYVHIFNQSTN--IMHDEWRRLLAKGEHSVDMFEQISSLTLDSLL 189

  Fly   183 -----CDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKT 242
                 |||       ..:.:....:.|..|:...:..|..:.....:.||..:.....:.:....
Zfish   190 KCTFSCDT-------HSQEKPRQYISAILDLSRLLVQRQHYLPYHWDWLYWRSAQGRRFQQACAV 247

  Fly   243 LQDFTNEIIAKR---------IEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-GRPLNSKEL 297
            :..||.:|:.:|         .|:|..     |.|....||....:|.||.:..| |..|.::|:
Zfish   248 VHQFTADIVQERRTQLDQQSDPESHPE-----NTGRYRKRKNTDLIDLLLLAKDDKGEGLTNEEI 307

  Fly   298 YEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDA---TFQEISQMK 359
            ......|||.|||||.|.:|:..|.|:.:||.|.:...|.|:::.:    ||.   .::::||:.
Zfish   308 KAHADMFMFAGHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLAD----RDTHTIGWEDLSQLT 368

  Fly   360 YLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD-LVPKGTTLNLGLVMLGYNEKVFKDPHKFRPER 423
            :..:.|||:.|::..|..:.|:..::....|| ::|.|....:.:..:..|.:|:.||..|.|.|
Zfish   369 FTTMCIKESLRLHSPVLALTRYYSQNMKTPGDCVIPHGCLCLISIYGVHRNPQVWPDPLVFDPTR 433

  Fly   424 FE---LEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTI 485
            |:   .:...|..::||||||||||||.||:.|:|.||:..:..|::||.
Zfish   434 FDPHNSDSRSPHAFIPFSAGPRNCIGQNFAMAEMKVVVALTLARFKILPG--------------- 483

  Fly   486 GLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524
                     ..|.|..|.      |.|::|.|:.:..:|
Zfish   484 ---------PKPVRRLYQ------LVLRAEGGMILHFQE 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	132/479 (28%)
cyp4f3	NP_001083010.1	CYP4F	59..504	CDD:410772	136/492 (28%)