DRSC/TRiP Functional Genomics Resources

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Protein Alignment Socs44A and SLA2

DIOPT Version :10

Sequence 1:NP_523659.1 Gene:Socs44A / 35786 FlyBaseID:FBgn0033266 Length:342 Species:Drosophila melanogaster
Sequence 2:NP_115590.1 Gene:SLA2 / 84174 HGNCID:17329 Length:261 Species:Homo sapiens


Alignment Length:125 Identity:32/125 - (25%)
Similarity:56/125 - (44%) Gaps:21/125 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   189 WYWGEISRRDSQR--QLSDKPTGSFLVRDSETSGSQFTLSFRIVNVT-----LHYRLEYRDNFWH 246
            |.:..:||..::.  .|...|.|:||:|:|:|....::||.|:....     .|||:...||.|.
Human    94 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWL 158

  Fly   247 F--EELKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQP---------PFPV-ILKYPLS 294
            :  ..|.:.|:..:::......  |:..|.:|.|..:|.         |.|| :.:.||:
Human   159 YISPRLTFPSLQALVDHYSELA--DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLN 216

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Socs44ANP_523659.1 SH2_SOCS_family 188..266 CDD:198178 22/85 (26%)
SOCS 293..333 CDD:470605 1/2 (50%)
SLA2NP_115590.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..31
SH3_SLAP2 36..90 CDD:212944
SH2_SLAP 83..186 CDD:198207 23/93 (25%)
SLA C-terminal 195..261 5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

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