Protein Alignment sut1 and MPH3

DIOPT Version :9

• Sequence 1: NP_523658.1
• Gene: sut1 / 35774
• FlyBaseID: FBgn0028563
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_012694.1
• Gene: MPH3 / 853625
• SGDID: S000003921
• Length: 602
• Species: Saccharomyces cerevisiae
• Alignment Length: 543
• Identity: 119/543 - (21%)
• Similarity: 203/543 - (37%)
• Gaps: 92/543 - (16%)

  Fly    18 NRV--ELLSAQTDPSQKPRWGNLLLLVALATTFGGA------VST-----GYCIGVINAPSKLMK 69
            |:|  |:..|..|..:.......:.|.....|:..|      |||     ||...::.|
Yeast    62 NKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGA------ 120

  Fly    70 VWCNQTLHDTYGSNLSAGG---LDLLWSCVVSVFLVGGAIGSLGGAG-AANKFGRKACFLICGAL 130
            .:........:||.....|   :...|...:::..:.|.|..|...| :.:..|.:...:|  ||
Yeast   121 FYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLII--AL 183

  Fly   131 FTVGAVLF--FFCRAASSVEMLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTL--------- 184
            |.:.|..|  :||   :|:.|:.:|:.:.|:..|........|.||:.|:|||..|
Yeast   184 FFLAAFTFILYFC---NSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWL 245

  Fly   185 -GVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFLILV-CYLPSYLFPESPKFLYIVKG 247
             |...|.|:        :.:....:...:|.:....|..:::.| ..|..:..||||.:| :.||
Yeast   246 FGQLFAAGI--------MKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWL-VKKG 301

  Fly   248 NRAAAKRELQRL---RGKDAEELIAQEM----AEMEAESNAKVQTSSFCDVLRDPRLTLPLIIVC 305
            ....|:|.|:|.   :|.:.|.|:..|:    ..::.|.....:..|:.|...|........|.|
Yeast   302 RFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRITC 366

  Fly   306 CFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMF 370
            ....||...| :.:..||...:||||:||..:...::...||.:..:.|..|......|..|..|
Yeast   367 LCWAGQATCG-SILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAF 430

  Fly   371 SCALCSVFLFTIAFVLFYIDQVSWFAIACI----------VCIMGYIFFYQFGLGPIPYFIGAEL 425
            ..|..::..|.|.            .:.|.          ..:|...|||..|:.|:.:.:.:|:
Yeast   431 GLAFQTIVFFIIG------------GLGCSSTHGSKMGSGSLLMAVAFFYNLGIAPVVFCLVSEM 483

  Fly   426 FEVAPRS--------VAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCVLLFLLTKFY 482
                |.|        :|.:..::.|..|:.:|.......:..|||.....:.:.|....:.....
Yeast   484 ----PSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVD 544

  Fly   483 LPETRGRDPSEVAPLVSKGFRSK 505
            ||||.|:...|:..|...|..::
Yeast   545 LPETAGKTFVEINELFKLGVSAR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	MFS_GLUT_Class1_2_like	48..489	CDD:340915	108/493 (22%)
MPH3	NP_012694.1	SP	72..556	CDD:273317	112/520 (22%)