DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and HXT9

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	508	Identity:	135/508 - (26%)
Similarity:	226/508 - (44%)	Gaps:	61/508 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DPSQKPRWG-NLLLLVALATTFGGAV---STGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGG 88
            |..|||... ..:.::.|...|||.:   .||...|.:|. |..::.:..:....||..:....|
Yeast    49 DLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNL-SDFIRRFGQKNDKGTYYLSKVRMG 112

  Fly    89 LDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVE---ML 150
            |      :||:|.:|.|||.:..:...:.:||:...:...|::.||.::     ..:|:.   ..
Yeast   113 L------IVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILI-----QITSINKWYQY 166

  Fly   151 VIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWH 215
            .|||.:.||..|.:....||.:|||||..:||||.....:..|.|:.:|...:    :||:: :|
Yeast   167 FIGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTN----YGTKN-YH 226

  Fly   216 YALTAYMFLILVCY------LPSYLF-PESPKFLYIVKGNRAAAKRELQRLR--GKDAEELIAQE 271
            .| |.:...:.:|:      :...:| ||||::| |..|....|||.|.:..  ..|...|:|:.
Yeast   227 NA-TQWRVGLGLCFAWTTFMVSGMMFVPESPRYL-IEVGKDEEAKRSLSKSNKVSVDDPALLAEY 289

  Fly   272 ---MAEMEAESNAKVQTSSFCDVLRDPRLTLPLIIV-CCFHGGQQLSGINAIFYYSVSIFEKAGL 332
               .|.:|.|..|  ..:|:.::|.........::: ......|||:|.|..|||..:||:..||
Yeast   290 DTIKAGIELEKLA--GNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGL 352

  Fly   333 STVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCA--LCSVFLFTIAFVL-------FY 388
            .  |:...::..|.:|...|.:..:.:.:..|||.:::..|  ||...:|....|.       .:
Yeast   353 K--DSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSH 415

  Fly   389 IDQVSWFAIAC-IVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGIS 452
            .|..|..|..| ||..|.:||.:........|.|.:|.|.:..:|..|::.:.|:|...|:|...
Yeast   416 QDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFF 480

  Fly   453 FPLLQ---NAWGAFVFLPFSITC-VLLFLLTKFYLPETRGRDPSEVAPLVSKG 501
            .|.:.   |.:..:|||    .| |..:....|::|||:|....||..:..:|
Yeast   481 TPFITGAINFYYGYVFL----GCLVFAYFYVFFFVPETKGLTLEEVNTMWLEG 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	125/471 (27%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	110/415 (27%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	130/488 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840