Protein Alignment sut1 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_523658.1
• Gene: sut1 / 35774
• FlyBaseID: FBgn0028563
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 167/483 - (34%)
• Similarity: 256/483 - (53%)
• Gaps: 16/483 - (3%)

  Fly    26 QTDPSQKPRWGNLLLLVALAT---TFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAG 87
            |.|.|.|.  |.|.|::||||   .||.:...||.:..:|:|:.||:.:.|:|.:...|..:...
Human     3 QQDQSMKE--GRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDF 65

  Fly    88 GLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVI 152
            .|.||||..||:|..||.||||......||||||...|.......|.|:|....|.|:|.|:::|
Human    66 PLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIII 130

  Fly   153 GRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWH-- 215
            .|.:||:.:|:.:..:||||.|:||..|||.|||...:.:|.|::|.|:..|.|:....|.|.
Human   131 SRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195

  Fly   216 YALTAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIAQEMAEMEAESN 280
            ..||.....:.:..||  .|||||::|.|.|.:.||||:.||.|||.|:   :.:|:||:..|..
Human   196 LGLTGVPAALQLLLLP--FFPESPRYLLIQKKDEAAAKKALQTLRGWDS---VDREVAEIRQEDE 255

  Fly   281 AKVQTSSFCDVL---RDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANL 342
            |: :.:.|..||   |...|...|:.:....|||||||:|||:||:..|:..||:.....|:...
Human   256 AE-KAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTA 319

  Fly   343 GAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCIMGYI 407
            |.|.:|:.::....:::....||.|::...::|.:....:...|...|.|||.....|||::.|:
Human   320 GTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYV 384

  Fly   408 FFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITC 472
            ..:..|..|||..:..|:|..:.|..|..:|....|..||.:|:.||.:|...|.:.|:.|::.|
Human   385 IGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVIC 449

  Fly   473 VLLFLLTKFYLPETRGRDPSEVAPLVSK 500
            :|..:.....:|||:.:...|:..:.:|
Human   450 LLTTIYIFLIVPETKAKTFIEINQIFTK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	MFS_GLUT_Class1_2_like	48..489	CDD:340915	154/445 (35%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	154/453 (34%)