DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and AgaP_AGAP005238

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_314142.4	Gene:	AgaP_AGAP005238 / 1274945	VectorBaseID:	AGAP005238	Length:	492	Species:	Anopheles gambiae

Alignment Length:	486	Identity:	254/486 - (52%)
Similarity:	336/486 - (69%)	Gaps:	11/486 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PRWGNLLLLVALA--TTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGGLDLLWSC 95
            |..|..|.||.|.  |:.|.::..||.|||||||::.:|.|.|:|::..|...||...|..:.:.
Mosquito     6 PESGWTLRLVGLGAITSLGASIPVGYNIGVINAPTEFIKHWSNETIYRRYNVLLSDNSLRAIIAS 70

  Fly    96 VVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLA 160
            ::|:.|:||.||||.||..|:|:|||..||.|..|.|.||:.|..|||.||||:|::||.:||||
Mosquito    71 IISIALIGGVIGSLQGAYLADKYGRKKSFLCCALLLTGGALCFLCCRAVSSVELLLLGRLLVGLA 135

  Fly   161 SGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFLI 225
            |||.|..:||||:||:|:.|||.:||...:|:|.||||.||.||....|||:.|||||..:..|.
Mosquito   136 SGLTTGVIPMYLAEVSPIKLRGAMGVLCPLGLTTGVVVAQVASLEQALGTEEHWHYALGCFAVLN 200

  Fly   226 LVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKD--AEELIAQEMAEMEAESNAKVQ---- 284
            |.||...:..|||||:||.|||::|.:.|.:::|.|:.  .::.|..:|.....::....|
Mosquito   201 LFCYAFYFWIPESPKYLYSVKGDQAGSLRAIRKLFGRHTIGDDYIKLQMECANGQNGPSAQEDGQ 265

  Fly   285 ---TSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGC 346
               ..|...|:|||.|||||::||...||||||||||:|:|||||||..|.|:..|::||||.||
Mosquito   266 PQANRSLWSVVRDPTLTLPLVLVCALQGGQQLSGINAVFFYSVSIFESVGFSSQAAKFANLGVGC 330

  Fly   347 LNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCIMGYIFFYQ 411
            |||..||.||.|||:||||||.:.||:.|::.||.:...:.:|..:.||:..||..|:.||.|||
Mosquito   331 LNLFASLFGPLLMARCNRRTLCLLSCSSCAIILFVLTLSIHFIHLIDWFSYVCIGTILLYIIFYQ 395

  Fly   412 FGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCVLLF 476
            |||||||:|||:|||::.||..||::|||:||.|||::|::||.|||.||||||||||||||||.
Mosquito   396 FGLGPIPFFIGSELFDLGPRPTAMALGSLSSWGCNFVVGMAFPTLQNIWGAFVFLPFSITCVLLT 460

  Fly   477 LLTKFYLPETRGRDPSEVAPLVSKGFRSKVK 507
            :|.|||||||||::.::|.|.|:.||||:||
Mosquito   461 VLIKFYLPETRGKEVTDVVPKVAHGFRSRVK 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	238/450 (53%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	212/394 (54%)
AgaP_AGAP005238	XP_314142.4	Sugar_tr	30..473	CDD:278511	236/442 (53%)
AgaP_AGAP005238	XP_314142.4	MFS	78..468	CDD:119392	212/389 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	516	1.000	Domainoid score	I1095
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80456
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27136
OrthoDB	1	1.010	-	-		D22522at7147
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	1	1.000	-	-		mtm9608
Panther	1	1.100	-	-	LDO	PTHR23503
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11825
TreeFam	1	0.960	-	-
	12	11.890