Protein Alignment lig and ubap2l

DIOPT Version :10

• Sequence 1: NP_001260795.1
• Gene: lig / 35771
• FlyBaseID: FBgn0020279
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: XP_005159453.1
• Gene: ubap2l / 100034477
• ZFINID: ZDB-GENE-060503-244
• Length: 1212
• Species: Danio rerio
• Alignment Length: 1388
• Identity: 373/1388 - (26%)
• Similarity: 548/1388 - (39%)
• Gaps: 372/1388 - (26%)

  Fly    50 QDASKTDKPEKAQPKATTEQLRIAQITNSTTEDPQINEKVLLLLTMTQRSEEEVCCALNECDYDL 114
            |..:::....|.:|:||.||:|:||:. |...|....|||..|:.:|.:.::|...||::|:.|:
Zfish    18 QGQTQSQSQHKQRPQATAEQIRLAQMI-SDHNDADFEEKVKQLVDITGKDQDESMIALHDCNGDV 81

  Fly   115 EAAANFLIEELPQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNGNADRREKSRNRSSNRGGT- 178
            ..|.|.|:|..|.....:...|:|......:|....||    :|..|.:|..: |:.:..|||.
Zfish    82 NRAINVLLEGSPDTDSWEMVGKKKVSGQKESAQTDGGD----EGKENRERGGE-RDVARRRGGAP 141

  Fly   179 ---RGSSDSRGWRGRETRENERNQRESREPWSGQNAG--QDRGDDRANDNYRGQRNGGGRSGPGG 238
               ||:|     ||||.|..|..       ..|..||  ..||.:|.       |.|.||...||
Zfish   142 RRGRGAS-----RGREFRGQENG-------LDGAKAGGVAGRGTERG-------RRGRGRGRAGG 187

  Fly   239 GGRGGGFVSRSGRGGGRMGGRTGGPR----GDRGSGGP--------------GGAYGSGRGGNAN 285
            .||.||..|..|     ||....|||    ||..:..|              .|:..|..|....
Zfish   188 AGRRGGRFSAQG-----MGQIDKGPRYDFSGDESTFNPADYTEPAQTEESYTSGSTWSNTGNLEP 247

  Fly   286 EDHHEVELWDNTIAQNAEKQQQAHDDAW----GDWNNEEYEGSLKDSKVFTTSNLAT----QSAA 342
            ||.:.:|..... ..|...:..:...||    .:|..|::...|.::|:||.|::|:    |...
Zfish   248 EDGNRLEFTGGE-GTNYPLKFDSAPGAWRTATEEWGTEDWNEDLSETKIFTASSVASMPIPQENV 311

  Fly   343 NVVSGTGASVTAV-----PAAAGTEISA-----PPGLEHQLV----QQGSHLEESSSSGPAA--- 390
            .:.:|....:..:     |:::..|.::     |..|...||    :|.|.|.:||||.|.:
Zfish   312 TITAGQRIDLAVLLGKTPPSSSEAEPASLEGPQPQSLSQSLVFSNSKQTSSLSQSSSSAPYSQHN 376

  Fly   391 -----------VTPPATLSGSATTP---LLQYSAAVSNPPPQLQSQGTQSG---AGTG---ASAA 435
                       |..|.|.:|.:||.   |.|:..|  ....||.:|.:|||   ||..   .|.:
Zfish   377 MVSMLGKGFGDVGDPKTTTGGSTTGSQFLEQFKTA--QALAQLAAQHSQSGPPNAGPSTWDTSPS 439

  Fly   436 AGGGAGSTPSSFVSASPDTFSSAASAAATLVHQAQKQQQLQQQTTPIKPSATLSV-EQSQYFNSL 499
            |.|.....|.:....||.|.......|:|..  :.....||.:||  .||:|.:: .||...:||
Zfish   440 ALGQYDMKPQTEPVHSPFTKRQPYQPASTTT--SMMDAFLQDKTT--GPSSTSALPPQSTQASSL 500

  Fly   500 ASQGVSPGSVPVQSAPAGYAQNPVAAYSQTSTSVGVSQYPNTYANVFASGTAAGAGTAEQSQQQP 564
            |....:|.|.|:.:||.          .|.|:|.             |...|:.....:|.:.:.
Zfish   501 AQAITTPVSKPMGAAPG----------QQNSSSP-------------ADPQASSPLPLQQHKLKQ 542

  Fly   565 QIRRARVKLPPPSKIPASAVEMPGDNALNNIGYLDVQFGALDFGTDDGFEP-LPEKVGS---GFS 625
            |.:||.:    .:||||.||||||.   .:|..|::|||||.||:    || |||...|   ..:
Zfish   543 QKKRASI----TTKIPALAVEMPGS---ADISGLNLQFGALQFGS----EPVLPEYDASAAVATT 596

  Fly   626 IDGQQQQ------------------QQPDDYQSKSQQQQQVTLAAGLQSSQISDALNAAGYTSRS 672
            ..|.|.|                  .|.:.|:|::.|.::  ....:.||...|.....|::|..
Zfish   597 TPGNQGQNSLYTSASNEQATALSNPSQMELYESRANQTRR--YPPSVSSSPQKDMQTKNGFSSIQ 659

  Fly   673 TSQQQQGVS-----------SAVNATIDQLTK-SDPYGQTGGSGNAYQNAYQSSGASK---TASG 722
            |||..:..:           |.|..::..:.. :||                |||.:.   |::.
Zfish   660 TSQSLEAAAGSAVPVKPVSESVVPPSVSNMVSLADP----------------SSGPTSLLTTSNQ 708

  Fly   723 FPTTAPG--GYSSSTYANVQSSVANSYQQQGYGSYQPSSYQQQAGSGAQSGTGAVSGGGGTATQN 785
            .|.:|..  ..|.|:.|...::..::.|    .|..|||.:       .|.|..:.
Zfish   709 TPLSALSHEDVSPSSLATQHNNSLSTQQ----NSLAPSSVR-------TSNTSLLH--------- 753

  Fly   786 IPVGGSSSQNSTSVSTSSGVSSNSGSTGNGGVVSGQTGANQAAVSNNNSVSGSSSVSNVTAGVAS 850
             ||.|.||.:|:|.|.|:...|                          ||...||:::|.....|
Zfish   754 -PVDGDSSLHSSSFSVSAVAPS--------------------------SVPPPSSITSVAPVSHS 791

  Fly   851 GNVAGVGGGVSQSGVSSGVGVPGGSASSVGVNVNNNSSSASSVGAATVAQTATGTTAAVLASLTN 915
            |.|                 ||..|.|.|        |:.||:|..::|.   |...||::.:..
Zfish   792 GPV-----------------VPPSSVSLV--------STQSSMGPVSLAM---GLNNAVVSMVPP 828

  Fly   916 KNTSSSNSSGSGGSAATTTGNASGQGAGASTGGVGSSSGAGGAGSGGGSGSGLVPTNIQ------ 974
            ...:||:||.:..|||.::.:.|...|                      .||..|.|:.
Zfish   829 SAAASSSSSAASASAAPSSASLSRSTA----------------------ASGKAPPNLPPGVPPL 871

  Fly   975 MVSQYIQT-GL--PYYQQPVYSYEELQMMQQRVPHVQGYYDLNY--PPASLGAGRDNLGSVTYSA 1034
            :.:.||.. ||  ||..| ||.|::|||:|.|:|  ..||.:.:  |..:|......|.|..|||
Zfish   872 LPNPYIMAPGLLHPYPPQ-VYGYDDLQMLQTRIP--LDYYSIPFATPTTALTGREGGLTSNPYSA 933

  Fly  1035 MNDGRFARTDNNSSPVGNVSSTMSQQAGSSA------PMLN--VPYAYFY-------GGNVMPGS 1084
            .:..:|.|.| .|||....:....||..:..      |.||  :|..|.|       |...:|.:
Zfish   934 GDLSKFGRND-ASSPAPATTLAQPQQTQTQTHHTTQQPFLNPALPPGYSYTSLPYYTGVPGLPNT 997

  Fly  1085 FQYGTPAIYPQIPAAN---------TASGQQFPKPSYSAGYG----STSYDTLSQTTQ---DYSK 1133
            |||| ||::|..|.::         .||...|.:.|   |||    ||.|:.|.|.:.   |:.|
Zfish   998 FQYG-PAMFPVAPTSSKQHGVNVGVNASATAFQQAS---GYGSHGYSTGYEDLGQASAGSGDFCK 1058

  Fly  1134 GGYSSSV-----------NQQSKTQTVSNQSQAGTGSDLTSSMYGKGHVA---LNKVNSYEKQSF 1184
            ||||::|           ...::.:..|:.:..|.|..:|||..|...::   ..|..|:|||.|
Zfish  1059 GGYSTAVAAAAAAAAAAAAASAQNKPASSVTGPGVGVSVTSSNTGVPDISGSVYTKTQSFEKQGF 1123

  Fly  1185 HSGTP-PPFNMP---------NTQTAGGTSAQPYGMYLPMPAAGHHNMIHQPIHQDSNS-AGQRQ 1238
            |:||| ..|::|         |...|.|.:..||...|......|..|:|..:.||..| :|||.
Zfish  1124 HTGTPSASFSLPSALGSAGPINPPAAAGYAPAPYMHILTPHQQPHSQMLHHHLQQDGQSGSGQRS 1188

  Fly  1239 QSTS--QSKSAGKQGYSPSYWAG 1259
            |:.|  |.....|.||:...|.|
Zfish  1189 QNASIQQKSQINKSGYNSYNWGG 1211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lig	NP_001260795.1	PRK12678	16..>229	CDD:237171	54/184 (29%)
		UBA_UBP2_like	85..122	CDD:270463	12/36 (33%)
		DUF3697	575..607	CDD:372135	17/31 (55%)
ubap2l	XP_005159453.1	UBA_UBP2_like	52..89	CDD:270463	12/36 (33%)
		DUF3697	551..578	CDD:372135	17/29 (59%)
		PLN03188	<585..>751	CDD:215621	38/194 (20%)