Protein Alignment: Odc1 and ODC1

• Sequence 1: NP_477052.2
• Gene: Odc1
• FlyBaseID: FBgn0013307
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001274118.1
• Gene: ODC1
• HGNCID: 8109
• Length: 461
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 178/393 (45%)
• Similarity: 241/393 (61%)
• Gaps: 37/393 (9%)

  Fly    29 LDQALN------------ICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLGAGFD 81
            |||.:|            :.||..:.:|...|.|.|||:.|||||||||...:|:.||..|.|||
Human    24 LDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFD 88

  Fly    82 CASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNSNLIV 146
            ||||.|::||....|.|||||:||||:.||.::||..:.|...|.|:|.|:.|:...:|.:.|::
Human    89 CASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVL 153

  Fly   147 RFKSEAKEAQCPLGDKFGCDADVDAAALML-LAKSLELKVTGTSFHVGSGCSELQAYDRAIKKAK 210
            |..::..:|.|.|..|||  |.:..:.|:| .||.|.:.|.|.||||||||::.:.:.:||..|:
Human   154 RIATDDSKAVCRLSVKFG--ATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDAR 216

  Fly   211 NLFKFGALLGYDMDFLDIGGGFPGSDDV--KFEKIAESVNTSVQRHFP-DERVHIIAEPGRFFVA 272
            .:|..||.:|:.|..||||||||||:||  |||:|...:|.::.::|| |..|.|||||||::||
Human   217 CVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVA 281

  Fly   273 AACTLVCKIHAKR-EIRNEAGKLD-------TVMYYLNDGVYGSFNCILYDHQVVIAEHYLDNAE 329
            :|.||...|.||: .::.:.|..|       |.|||:|||||||||||||||     .|.....:
Human   282 SAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDH-----AHVKPLLQ 341

  Fly   330 SLP-----HLKSLIWGPSCDALDKISEDLHLPNLNRGDLLGFRNMGAYTMPIASAFNGFEVPKTL 389
            ..|     :..|.||||:||.||:|.|...||.::.||.:.|.||||||:..||.||||:.| |:
Human   342 KRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRP-TI 405

  Fly   390 YF 391
            |:
Human   406 YY 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Odc1	NP_477052.2	LysA	16..391	CDD:223098	178/391 (46%)
		PLPDE_III_ODC	30..391	CDD:143482	177/390 (45%)
ODC1	NP_001274118.1	PLPDE_III_ODC	37..408	CDD:143482	174/380 (46%)
		LysA	40..408	CDD:223098	174/377 (46%)
		Pyridoxal phosphate binding. {ECO:0000244|PDB:2OO0, ECO:0000269|PubMed:17407445, ECO:0000269|PubMed:26305948, ECO:0000269|PubMed:26443277}	274..277		3/3 (100%)
		Substrate binding. {ECO:0000250|UniProtKB:P07805}	331..332		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C37137192
eggNOG	1	0.900				E1_COG0019
Hieranoid	1	1.000
Homologene	1	1.000				H1906
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2494
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D306092at33208
OrthoFinder	1	1.000				FOG0001021
OrthoInspector	1	1.000				T130155
orthoMCL	1	0.900				OOG5_126750
Panther	1	1.100			LDO	PTHR11482
Phylome	1	0.910		0.662	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R297
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	14	13.800