Protein Alignment Hey and bhlhe40

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_997844.2
• Gene: bhlhe40 / 324413
• ZFINID: ZDB-GENE-030131-3133
• Length: 403
• Species: Danio rerio
• Alignment Length: 310
• Identity: 79/310 - (25%)
• Similarity: 117/310 - (37%)
• Gaps: 98/310 - (31%)

  Fly    86 EQISPSEPGSCQLMSR-------------------KKRRG----------------VIEKKRRDR 115
            |:|:.::|..|  ||:                   |.|||                :||||||||
Zfish     2 ERITSAQPPPC--MSKHPSLDISDMQGMDFPMYVYKPRRGMKRSEDSKDTYKLPHRLIEKKRRDR 64

  Fly   116 INSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSL------QSKTLDSL---------SY 165
            ||..:.:||.|:|...:......||||.:|:||::|:|:|      |.:.:.||         ..
Zfish    65 INECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALNNLLEQQQQKIISLQNGLQIGEQGN 129

  Fly   166 DPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQ----------RELS 220
            .|...:.:....||..||.||.::|...|.|  :|.....::.|||....:          .|.:
Zfish   130 GPSENSEEMFRSGFHLCAKEVLQFLANQETM--RDLTTAHIIEHLQKVASELIQSPPSPRLDEPA 192

  Fly   221 AKSCAS---PGGWSPAAPSSSGYQPNCAAAPYQSYAAPA-------------------------N 257
            :|:..|   |.|..|.|  :.|:..||.....::|...:                         .
Zfish   193 SKAQESREKPSGLQPKA--AEGHAKNCVPVIQRTYPHSSEQSGSDTDTDSGYGGEYEKRDQKAQR 255

  Fly   258 PGAYVSSYPTLSASPSQQAQQLGGRTSVSRTSGSAVTESLPSHDL---HS 304
            |..||.....|..|.|.:.:| ....|....|.|:..|||..||:   ||
Zfish   256 PDCYVKESGALKYSSSIKEEQ-DEPPSKRPRSDSSEDESLSGHDVVGGHS 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	32/108 (30%)
		ORANGE	172..218	CDD:128787	13/55 (24%)
bhlhe40	NP_997844.2	bHLH-O_DEC1	37..126	CDD:381592	30/88 (34%)
		Hairy_orange	138..177	CDD:462193	13/40 (33%)