Protein Alignment Hey and Helt

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_006509452.1
• Gene: Helt / 234219
• MGIID: 3040955
• Length: 241
• Species: Mus musculus
• Alignment Length: 214
• Identity: 73/214 - (34%)
• Similarity: 100/214 - (46%)
• Gaps: 45/214 - (21%)

  Fly    95 SCQLMSRKK---RRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSLQ 156
            |.:|..||:   ...||||:||||||..|.||.:.||.|..||.|.||||||||::||::|::|.
Mouse     2 SDRLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALH 66

  Fly   157 SKTLDSLSYDPQRVA--MDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQREL 219
            |..........:.:|  .:|...|:.||...:..||.|:|.|:.:|....|:::.||   .:..|
Mouse    67 SADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQ---SKARL 128

  Fly   220 SAK-----------------SCASP--GGWSP---------AAPSSSGYQPNCAAAPYQSYAAPA 256
            .|:                 ..|||  .|.||         |.|.|..:.|..|.:|    |.|
Mouse   129 GAEPTFPPLSLPEPDFSYQLHAASPEFPGHSPGEATMFPQGATPGSFPWPPGAARSP----ALP- 188

  Fly   257 NPGAYVSSYPTLSASPSQQ 275
                |:||......||:||
Mouse   189 ----YLSSATVPLPSPAQQ 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	36/70 (51%)
		ORANGE	172..218	CDD:128787	13/45 (29%)
Helt	XP_006509452.1	bHLH-O_HELT	14..69	CDD:381414	32/54 (59%)
		Hairy_orange	86..127	CDD:462193	13/43 (30%)
		PLN02983	<147..>213	CDD:215533	21/66 (32%)