Protein Alignment Hey and Hey1

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001178774.2
• Gene: Hey1 / 155437
• RGDID: 621403
• Length: 299
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 134/401 - (33%)
• Similarity: 188/401 - (46%)
• Gaps: 132/401 - (32%)

  Fly    47 AHSNHSHGHSQGHSHGIGSLKRTL--SESDCDDLYSEESSKEQISPSEPGSCQLMSRKKRRGVIE 109
            ||.::|...|:        |..|:  .:...|:..:..|:...:||:.  |.|:::||:|||:||
  Rat     4 AHPDYSSSDSE--------LDETIEVEKESADENGNLSSALGSMSPTT--SSQVLARKRRRGIIE 58

  Fly   110 KKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSLQSKTLDSLSY-DPQRVAMD 173
            |:||||||:||:||:||||||:|||||||||||||||:||:|||.|.  |.....| |...:|||
  Rat    59 KRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLH--TAGGKGYFDAHALAMD 121

  Fly   174 YHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGG-----WSPA 233
            |..:|||||.|||||||..|||:|..||||:||:|||..:..|||.::   .:.||     |.
  Rat   122 YRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAAS---GAHGGLGHIPWG-- 181

  Fly   234 APSSSGYQPNCAAAPYQSYAAPANPGAYVSSYPTLSASPSQQAQQLGGRTSVSRTSGSAVTESLP 298
              |:.|:.|:.|                   :|.|                            ||
  Rat   182 --SAFGHHPHIA-------------------HPLL----------------------------LP 197

  Fly   299 SHDLHSDSSSQQQQQQQQQQQQQQQHQQQQHQQQQQRTQTTPQPTQQQHYTHDHSAVHSEQQV-- 361
            .:. |.::.                              ||..||:..|.....|| |.|...
  Rat   198 QNG-HGNAG------------------------------TTASPTEPHHQGRLASA-HPEAPALR 230

  Fly   362 --------PTYIELTNSNR--PAAIGSDSLSYSAAPQYPVSGLPGQDYNNSSVLQYATPNGA--- 413
                    |....:|::::  |..:.|.: |.||   :|.|      :::..:|..:||:.|
  Rat   231 APPSGGLGPVLPVVTSASKLSPPLLSSVA-SLSA---FPFS------FSSFHLLSPSTPSQAANL 285

  Fly   414 -KPYRPWGAEM 423
             |||||||.|:
  Rat   286 GKPYRPWGTEI 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	48/67 (72%)
		ORANGE	172..218	CDD:128787	29/45 (64%)
Hey1	NP_001178774.2	bHLH_SF	41..122	CDD:469605	53/84 (63%)
		ORANGE	120..166	CDD:128787	29/45 (64%)