Protein Alignment Hey and Hes5

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_006538625.3
• Gene: Hes5 / 15208
• MGIID: 104876
• Length: 415
• Species: Mus musculus
• Alignment Length: 289
• Identity: 74/289 - (25%)
• Similarity: 111/289 - (38%)
• Gaps: 79/289 - (27%)

  Fly    14 HW----GYAAGPGVVMPGATATTPQSHWVPPPQSHHSAHSNHSHGHSQGHSHGIGSLK----RTL 70
            ||    |.||.||...||..           |:.:.:.    ..|.....|...||::    |:|
Mouse   162 HWPPSVGTAAAPGPQAPGRC-----------PRLYRAG----VLGSRSRQSGTPGSVRSAPLRSL 211

  Fly    71 SESDCDDLYSEESSKEQISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEK-Q 134
            ..|....:.....:.|.:||.|       ..:.|:.|:||.||||||||:.:||.|:...:.: |
Mouse   212 IASRAPGMAPSTVAVEMLSPKE-------KNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQ 269

  Fly   135 GSAKLEKAEILQLTVEHLK---------------------------SLQSKTLDSLSYDPQRVAM 172
            .::|||||:||::.|.:||                           .|:..|..:.:..|:.:..
Mouse   270 PNSKLEKADILEMAVSYLKHSKGEPGACARLLLPADVAPTARAPLMPLRLPTAFAAAAGPKSLHQ 334

  Fly   173 DYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPSS 237
            ||. .|:..|..|..::|......|.|    ::|:.|.|             ..|   :||||:.
Mouse   335 DYS-EGYSWCLQEAVQFLTLHAASDTQ----MKLLYHFQ-------------RPP---APAAPAK 378

  Fly   238 SGYQPNCAAAPYQSYAAPANPGAYVSSYP 266
            ....|..|..|.:|.|..|......|..|
Mouse   379 EPPAPGAAPQPARSSAKAAAAAVSTSRQP 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	28/95 (29%)
		ORANGE	172..218	CDD:128787	11/45 (24%)
Hes5	XP_006538625.3	bHLH-O_HES5	236..292	CDD:381467	26/55 (47%)
		ORANGE	334..369	CDD:128787	11/52 (21%)