Protein Alignment Hey and Hes3

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_011248491.1
• Gene: Hes3 / 15207
• MGIID: 104877
• Length: 291
• Species: Mus musculus
• Alignment Length: 305
• Identity: 82/305 - (26%)
• Similarity: 122/305 - (40%)
• Gaps: 81/305 - (26%)

  Fly     7 VNAPSLHHWGYAAGPGVVMPGATATTPQSHWVPPPQSHHSAHSNHSHGHSQGHSHGIG---SLKR 68
            |.....|||             .|:.||             |...:.||.:.|.|.:|   :||.
Mouse    20 VKGAEKHHW-------------PASLPQ-------------HLYQASGHPELHHHHLGRPPALKA 58

  Fly    69 TLSE----SDC-----DDLYSEESS------KEQISPSEPGSCQLMSRKKRRGV----IEKKRRD 114
            ....    .:|     .||.|..|:      :...|.::|.:.:.....|..|:    :|||||.
Mouse    59 PCHSGGPPEECWLRSSQDLASRHSAWAPSPHRGTASVAQPAASERSGVLKGMGISKPLMEKKRRA 123

  Fly   115 RINSSLTELKRLVPSAYEKQ-GSAKLEKAEILQLTVEHLKSLQSKTLDSLSYDPQRVAMDYHIIG 178
            |||.||.:|:.|:...|..| ...|||||:||:|:|::::|||: :|..|...|..|  ||. .|
Mouse   124 RINVSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYMRSLQN-SLQGLWPVPSGV--DYP-SG 184

  Fly   179 FRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGG-----------WSP 232
            |:.....|::.|...||   ...||..|:      :|:||.|....|:|..           |:|
Mouse   185 FQGGLRGVSQRLRPGEG---DSGLRCPLL------LQRREGSTTDSANPQATSVLNPCLPAIWAP 240

  Fly   233 AAPSSSGYQPNCAAAPYQSYAAPANPGAYVSSYPTLSASPSQQAQ 277
            :..:...:.|       || ..|...|...||...::..|:...|
Mouse   241 SRAAGGSHSP-------QS-PLPLPGGLLESSTDVVAPHPASNCQ 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	29/72 (40%)
		ORANGE	172..218	CDD:128787	12/45 (27%)
Hes3	XP_011248491.1	bHLH-O_HES3	117..171	CDD:381503	27/54 (50%)