Protein Alignment Hey and Hes2

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_032262.2
• Gene: Hes2 / 15206
• MGIID: 1098624
• Length: 157
• Species: Mus musculus
• Alignment Length: 164
• Identity: 54/164 - (32%)
• Similarity: 81/164 - (49%)
• Gaps: 26/164 - (15%)

  Fly   101 RKKRRGVIEKKRRDRINSSLTELKRLVPS--AYEKQGSAKLEKAEILQLTVEHLKSLQSKTLDSL 163
            ||..:.::||:||.|||.||::||.||..  ..|...|:|||||:||::||..|:...:....|.
Mouse    14 RKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATLYSSA 78

  Fly   164 SYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDP-LRLRLMSHLQYFVQQRELSAKSCASP 227
            :..|    ::.::.|:|.|.|.:||.|   ....:.:| :..||:.||    :||.:|..   ||
Mouse    79 APGP----LNSYLEGYRACLARLARVL---PACSVLEPAVSARLLEHL----RQRTVSDD---SP 129

  Fly   228 GGWSPAAPSSSGYQPNCAAAPYQSYAAPANPGAY 261
            ....|.||         |.||......|.:.|.:
Mouse   130 SLTLPPAP---------APAPSPPVPPPGSSGLW 154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	27/63 (43%)
		ORANGE	172..218	CDD:128787	13/46 (28%)
Hes2	NP_032262.2	bHLH_SF	10..73	CDD:469605	27/58 (47%)
		ORANGE	85..123	CDD:128787	13/44 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		11/43 (26%)
		WRPW motif	154..157		0/1 (0%)