Protein Alignment: Nup44A and SEH1L

• Sequence 1: NP_610343.1
• Gene: Nup44A
• FlyBaseID: FBgn0033247
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_011524044.1
• Gene: SEH1L
• HGNCID: 30379
• Length: 441
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 194/367 (53%)
• Similarity: 254/367 (69%)
• Gaps: 36/367 (10%)

  Fly     1 MFDVEPIIADHKDVIHDVVFDYYGRRMATCSSDQTVKIWDEDGQGKWNVTSSWKAHSGSIWRVSW 65
            ||....|.|||||:||||.||::|||||||||||:||:||:...|.|:.|:|||.||||:|||:|
Human     1 MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSESGDWHCTASWKTHSGSVWRVTW 65

  Fly    66 AHPEFGQVVATCSFDRTASVWEEVIGEKVSSTNTPTR---RWVRRTTLVDSRTSVTDVEFAPKYL 127
            ||||||||:|:|||||||:||||::||    :|...|   .||:||||||||||||||:||||::
Human    66 AHPEFGQVLASCSFDRTAAVWEEIVGE----SNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHM 126

  Fly   128 GLLLATASADGIIRIYEAPDIMNLSQWPVQHEISNKLPLSCLSWN-------------------- 172
            ||:|||.|||||:|||||||:||||||.:|||||.||..||:|||
Human   127 GLMLATCSADGIVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSRISKLIEKMNRAHLYNFH 191

  Fly   173 -TSTYMVTQLLAAGSDEAA-TPTGKVFLFAYSENSRKCVKIDTVNDITDPVTDVAFAPNAGRTFH 235
             .|:...:.::|.|||::: ....||.:|.|:||:||..|.:|:..:||||.|:|||||.||:||
Human   192 IPSSRAHSPMIAVGSDDSSPNAMAKVQIFEYNENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFH 256

  Fly   236 MLAVASKDLYIVNLRGV----TDATDISKLDIQTI-KFSEHNCPVWRVCWNMLATMLISTGDDGC 295
            :||:|:||:.|..|:.|    |.:...:|.:|..: :|..||..||||.||:..|:|.|:|||||
Human   257 ILAIATKDVRIFTLKPVRKELTSSGGPTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGC 321

  Fly   296 VRLWRMNYNRQWRCAAVLKAEGS--GPTYEPAPPTPTLATT 334
            ||||:.||...|:|..:||..||  ..:.:.....|:|.:|
Human   322 VRLWKANYMDNWKCTGILKGNGSPVNGSSQQGTSNPSLGST 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup44A	NP_610343.1	WD40	6..>309	CDD:225201	184/333 (55%)
		WD40	11..300	CDD:295369	178/319 (56%)
		WD40 repeat	16..55	CDD:293791	26/39 (67%)
		WD40 repeat	60..98	CDD:293791	26/38 (68%)
		WD40 repeat	118..159	CDD:293791	32/41 (78%)
		WD40 repeat	166..212	CDD:293791	19/68 (28%)
		WD40 repeat	221..267	CDD:293791	22/51 (43%)
		WD40 repeat	275..299	CDD:293791	17/24 (71%)
SEH1L	XP_011524044.1	WD40	11..328	CDD:225201	178/321 (55%)
		WD40	11..326	CDD:295369	178/319 (56%)
		WD40 repeat	15..55	CDD:293791	27/40 (68%)
		WD40 repeat	61..111	CDD:293791	35/54 (65%)
		WD40 repeat	116..149	CDD:293791	26/33 (79%)
		WD40 repeat	166..232	CDD:293791	19/66 (29%)
		WD40 repeat	242..287	CDD:293791	21/45 (47%)
		WD40 repeat	301..340	CDD:293791	23/39 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C31166521
eggNOG	1	0.900				E1_KOG2445
Hieranoid	1	1.000
Homologene	1	1.000				H68701
Inparanoid	1	1.050	400	1.000	Inparanoid score	I1910
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D375879at33208
OrthoFinder	1	1.000				FOG0003642
OrthoInspector	1	1.000				T1073045
orthoMCL	1	0.900				OOG5_130934
Panther	1	1.100			LDO	PTHR11024
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1316
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	14	13.800