DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nup44A and seh1l

DIOPT Version :10

Sequence 1:NP_610343.1 Gene:Nup44A / 35762 FlyBaseID:FBgn0033247 Length:354 Species:Drosophila melanogaster
Sequence 2:XP_012820038.1 Gene:seh1l / 496570 XenbaseID:XB-GENE-1015661 Length:416 Species:Xenopus tropicalis


Alignment Length:329 Identity:188/329 - (57%)
Similarity:251/329 - (76%) Gaps:16/329 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MFDVEPIIADHKDVIHDVVFDYYGRRMATCSSDQTVKIWDEDGQGKWNVTSSWKAHSGSIWRVSW 65
            ||....|.|||||:||||.||::|||||||||||:||:||:...|.|:.|:|||.||||:|||:|
 Frog     1 MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSENGDWHCTASWKTHSGSVWRVTW 65

  Fly    66 AHPEFGQVVATCSFDRTASVWEEVIGEKVSSTNTPTR---RWVRRTTLVDSRTSVTDVEFAPKYL 127
            ||||||||:|:|||||||:||||::||    :|...|   .||:||||||||||||||:||||::
 Frog    66 AHPEFGQVLASCSFDRTAAVWEEIVGE----SNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHM 126

  Fly   128 GLLLATASADGIIRIYEAPDIMNLSQWPVQHEISNKLPLSCLSWNTSTYMV-TQLLAAGSDEAAT 191
            ||:|||.||||::|||||||:||||||.:|||||.||..||:|||.|:... :.::|.|||: ::
 Frog   127 GLMLATCSADGVVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAVGSDD-SS 190

  Fly   192 PT--GKVFLFAYSENSRKCVKIDTVNDITDPVTDVAFAPNAGRTFHMLAVASKDLYIVNL----R 250
            |.  |||.::.|:||:||..|.:|:..::|||.|:|||||.||:||:||||:||:.|..:    :
 Frog   191 PNIMGKVQIYEYNENTRKYAKAETLMSVSDPVHDIAFAPNLGRSFHILAVATKDVRIFTMKPLRK 255

  Fly   251 GVTDATDISKLDIQTI-KFSEHNCPVWRVCWNMLATMLISTGDDGCVRLWRMNYNRQWRCAAVLK 314
            .::.:..::|.:|.|: :|..||..||||.||:..|:|.|:||||.||||:.||...|:|..|||
 Frog   256 ELSSSGGVTKFEIHTVAQFDNHNSQVWRVSWNITGTVLASSGDDGTVRLWKANYMDNWKCIGVLK 320

  Fly   315 AEGS 318
            .:|:
 Frog   321 GDGN 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nup44ANP_610343.1 WD40 <8..302 CDD:441893 177/304 (58%)
WD40 repeat 16..55 CDD:293791 25/38 (66%)
WD40 repeat 60..98 CDD:293791 26/37 (70%)
WD40 repeat 118..159 CDD:293791 30/40 (75%)
WD40 repeat 166..212 CDD:293791 20/48 (42%)
WD40 repeat 221..267 CDD:293791 21/50 (42%)
WD40 repeat 275..299 CDD:293791 15/23 (65%)
seh1lXP_012820038.1 WD40 <11..326 CDD:441893 183/319 (57%)
WD40 repeat 15..55 CDD:293791 26/39 (67%)
WD40 repeat 61..111 CDD:293791 34/53 (64%)
WD40 repeat 116..149 CDD:293791 24/32 (75%)
WD40 repeat 166..212 CDD:293791 19/46 (41%)
WD40 repeat 222..267 CDD:293791 19/44 (43%)
WD40 repeat 281..320 CDD:293791 22/38 (58%)

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