Protein Alignment: Nup44A and seh1l

• Sequence 1: NP_610343.1
• Gene: Nup44A
• FlyBaseID: FBgn0033247
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_012820038.1
• Gene: seh1l
• XenbaseID: XB-GENE-1015661
• Length: 416
• Species: Xenopus tropicalis
• Alignment Length: 329
• Identity: 188/330 (57%)
• Similarity: 251/330 (76%)
• Gaps: 16/330 (5%)

  Fly     1 MFDVEPIIADHKDVIHDVVFDYYGRRMATCSSDQTVKIWDEDGQGKWNVTSSWKAHSGSIWRVSW 65
            ||....|.|||||:||||.||::|||||||||||:||:||:...|.|:.|:|||.||||:|||:|
 Frog     1 MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSENGDWHCTASWKTHSGSVWRVTW 65

  Fly    66 AHPEFGQVVATCSFDRTASVWEEVIGEKVSSTNTPTR---RWVRRTTLVDSRTSVTDVEFAPKYL 127
            ||||||||:|:|||||||:||||::||    :|...|   .||:||||||||||||||:||||::
 Frog    66 AHPEFGQVLASCSFDRTAAVWEEIVGE----SNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHM 126

  Fly   128 GLLLATASADGIIRIYEAPDIMNLSQWPVQHEISNKLPLSCLSWNTSTYMV-TQLLAAGSDEAAT 191
            ||:|||.||||::|||||||:||||||.:|||||.||..||:|||.|:... :.::|.|||: ::
 Frog   127 GLMLATCSADGVVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAVGSDD-SS 190

  Fly   192 PT--GKVFLFAYSENSRKCVKIDTVNDITDPVTDVAFAPNAGRTFHMLAVASKDLYIVNL----R 250
            |.  |||.::.|:||:||..|.:|:..::|||.|:|||||.||:||:||||:||:.|..:    :
 Frog   191 PNIMGKVQIYEYNENTRKYAKAETLMSVSDPVHDIAFAPNLGRSFHILAVATKDVRIFTMKPLRK 255

  Fly   251 GVTDATDISKLDIQTI-KFSEHNCPVWRVCWNMLATMLISTGDDGCVRLWRMNYNRQWRCAAVLK 314
            .::.:..::|.:|.|: :|..||..||||.||:..|:|.|:||||.||||:.||...|:|..|||
 Frog   256 ELSSSGGVTKFEIHTVAQFDNHNSQVWRVSWNITGTVLASSGDDGTVRLWKANYMDNWKCIGVLK 320

  Fly   315 AEGS 318
            .:|:
 Frog   321 GDGN 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup44A	NP_610343.1	WD40	6..>309	CDD:225201	181/314 (58%)
		WD40	11..300	CDD:295369	175/300 (58%)
		WD40 repeat	16..55	CDD:293791	26/39 (67%)
		WD40 repeat	60..98	CDD:293791	26/38 (68%)
		WD40 repeat	118..159	CDD:293791	31/41 (76%)
		WD40 repeat	166..212	CDD:293791	20/49 (41%)
		WD40 repeat	221..267	CDD:293791	21/51 (41%)
		WD40 repeat	275..299	CDD:293791	16/24 (67%)
seh1l	XP_012820038.1	WD40	11..>308	CDD:225201	175/302 (58%)
		WD40	11..306	CDD:295369	175/300 (58%)
		WD40 repeat	15..55	CDD:293791	27/40 (68%)
		WD40 repeat	61..111	CDD:293791	35/54 (65%)
		WD40 repeat	116..149	CDD:293791	25/33 (76%)
		WD40 repeat	166..212	CDD:293791	20/47 (43%)
		WD40 repeat	222..267	CDD:293791	19/45 (42%)
		WD40 repeat	281..320	CDD:293791	23/39 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C31164376
eggNOG	1	0.900				E1_KOG2445
Hieranoid	1	1.000
Homologene	1	1.000				H68701
Inparanoid	1	1.050	397	1.000	Inparanoid score	I1804
OMA	1	1.010
OrthoDB	1	1.010				D375879at33208
OrthoFinder	1	1.000				FOG0003642
OrthoInspector	1	1.000				T1059136
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1316
TreeFam	1	0.960
	12	11.800