Protein Alignment Nup44A and sec13

DIOPT Version :10

• Sequence 1: NP_610343.1
• Gene: Nup44A / 35762
• FlyBaseID: FBgn0033247
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_988967.1
• Gene: sec13 / 394564
• XenbaseID: XB-GENE-944452
• Length: 320
• Species: Xenopus tropicalis
• Alignment Length: 350
• Identity: 101/350 - (28%)
• Similarity: 160/350 - (45%)
• Gaps: 75/350 - (21%)

  Fly     4 VEPIIADHKDVIHDVVFDYYGRRMATCSSDQTVKIWDEDGQGKWNVTSSWKAHSGSIWRVSWAHP 68
            :..:...|:|:|||...||||.|:||||||::|||:|....|: .:.:..:.|.|.:|:|:||||
 Frog     5 INTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVKNGGQ-ILIADLRGHEGPVWQVAWAHP 68

  Fly    69 EFGQVVATCSFDRTASVWEEVIGEKVSSTNTPTRRWVRRTTLVDSRTSVTDVEFAPKYLGLLLAT 133
            .:|.::|:||:||...:|:|..|           .|.:........:||..|.:||..|||:||.
 Frog    69 MYGNILASCSYDRKVIIWKEENG-----------TWEKTYEYTGHDSSVNSVCWAPHDLGLVLAC 122

  Fly   134 ASADGIIRIY----EAPDIMNLSQWPVQHEISNKLPLSC--LSWNTSTY--------------MV 178
            .|:||.|.|.    :.|       |.|: :|||...:.|  :||..|..              .:
 Frog   123 GSSDGAISILTYTGDGP-------WEVK-KISNAHTIGCNAVSWAPSVVPGSLVDQPSSQKPNYI 179

  Fly   179 TQLLAAGSDEAATPTGKVFLFAYSENSRKCVKIDTVNDITDPVTDVAFAPNAGRTFHMLAVASKD 243
            .:.::.|.|...    |:    :.|...:..:...:...:|.|.|||:||:.|.....:|..|:|
 Frog   180 KRFVSGGCDNLV----KI----WREEDGQWKEDQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQD 236

  Fly   244 LYIVNLRGVTDATDISKLDIQTIKFSEHNC-----------PVWRVCWNMLATMLISTGDDGCVR 297
                           .::.|.|...:..||           .||.|.|::.|.:|..:|.|..|.
 Frog   237 ---------------GRVYIWTSDDAATNCWNPKLLHKFNDVVWHVSWSITANILAVSGGDNKVT 286

  Fly   298 LWRMNYNRQWRCAA-VLKAEGSGPT 321
            ||:.:.:.||.|.: |.|.:|:..|
 Frog   287 LWKESVDGQWACISDVNKGQGAVST 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup44A	NP_610343.1	WD40	<8..302	CDD:441893	94/324 (29%)
		WD40 repeat	16..55	CDD:293791	18/38 (47%)
		WD40 repeat	60..98	CDD:293791	15/37 (41%)
		WD40 repeat	118..159	CDD:293791	16/44 (36%)
		WD40 repeat	166..212	CDD:293791	8/61 (13%)
		WD40 repeat	221..267	CDD:293791	12/45 (27%)
		WD40 repeat	275..299	CDD:293791	9/23 (39%)
sec13	NP_988967.1	WD40	<25..317	CDD:441893	92/329 (28%)
		WD40 repeat	61..101	CDD:293791	16/50 (32%)
		WD40 repeat	106..152	CDD:293791	20/53 (38%)
		WD40 repeat	160..208	CDD:293791	5/55 (9%)
		WD40 repeat	214..256	CDD:293791	14/56 (25%)
		WD40 repeat	264..290	CDD:293791	11/25 (44%)