DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG8726 and MDM1

Sequence 1:NP_610341.2 Gene:CG8726 FlyBaseID:FBgn0033244 Length:646 Species:Drosophila melanogaster
Sequence 2:NP_013603.1 Gene:MDM1 SGDID:S000004572 Length:1127 Species:Saccharomyces cerevisiae

Alignment Length:712 Identity:121/713 (17%)
Similarity:223/713 (31%) Gaps:277/713 (39%)


  Fly    12 LPI---------DDTQALSCEITAVQEVAGHTEYLLRVWRGASNKNYWTVLRRYNDFDRLDKSLR 67
            |||         |..:|:..::|..:..:.:.:..:.|   ..||||           ::.|||.
Yeast   152 LPIFNKHFSTFCDAREAVLSDLTLERHKSANIDLQIAV---EFNKNY-----------KIHKSLS 202

  Fly    68 V------SGIELPLPRKRIFGNMRPEFIAERKQAL------QEYINAVLMNPILASSLPAKRFVD 120
            :      ..||..: ||.:.|.:...|..:...:|      .|.:...:::|::.      :|.|
Yeast   203 LKPNALQKEIEKSI-RKTVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIF------KFTD 260

  Fly   121 PESY-------SQSFHD--HAVQNAMLCL----------RNDTTWSLGGSMGAIGWRLR------ 160
            |:|:       ||::.:  |.|......|          .||......|...:....|.      
Yeast   261 PDSWNLRIVSLSQNYFEEKHKVHKIRRMLSKELQDHRKVMNDVANKDVGEPSSEKLELNAEYTGK 325

  Fly   161 --KHY-----------------FKVTTKPPEKSSNKQLVKSGSQTHQSKHFAAGSSNGSGHSIDA 206
              :||                 :.:..|..:...|:.|.|...: ::.:...:.:...|..|...
Yeast   326 QFEHYLNQLDSLLDLSDIKYVAYSLALKIYQLKENEHLTKENLK-YKKRLLLSLNLIESKLSFPG 389

  Fly   207 GTLDPGSEVVAEWLEYGPDKFIDE----KEIGGIMKSLMGLQHPHIEPVLLAAHTENGCLVIRKF 267
            ..:|..|:.:|....| ||..:|.    ||:...:.|:                           
Yeast   390 SEIDTASKKLAREANY-PDLNMDNGIVLKEMASFLTSI--------------------------- 426

  Fly   268 HKHGTLKDVL-----------CMAANPK---NTFL------SKYGNP----------KGRTALSM 302
                ||||::           .:.:.|:   :|||      ..:.||          .|.:.:|.
Yeast   427 ----TLKDIVDDSEFLPFFESFLGSVPETQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGIST 487

  Fly   303 KQVATYG------------KQILEAL---IFLHSKGYAYGH-------LHSGNIVIVDDCVKLLD 345
            .|:....            |.:.|.|   |.|....:...:       .....:::..:.:|.||
Yeast   488 MQLQEISSKFFHNNNLQNMKLLDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLD 552

  Fly   346 IENFLLGVPAFYR-PFFMQH-SKIHAIETIDVYCFGHVLFEM-AMGYPLQESVVRQ--------- 398
             :.||   |.|.: |.|::. |..|.|.| |:|  .|.|..: .:..|.|..:::.         
Yeast   553 -DRFL---PLFKKTPSFLKMLSTSHIIST-DIY--AHFLSRIGGVNNPEQNKIIKDNVKTDFMNP 610

  Fly   399 --------ITECPEALKCLLESILSKEACK------AGLPTLEQLLG------------------ 431
                    ||:.       |::|::....|      :..|...||.|                  
Yeast   611 VRIFANPGITDA-------LDNIVNGSGSKPHKSRISSNPRYSQLFGSENDNIFKDKLFDDENDN 668

  Fly   432 ------------HRFFLQYASTESAGAAANAEKPYFKLSLNAKELLKQAAIKSENRLRDE----- 479
                        |...::..|..|..:..|..:.|                 ..|..||.     
Yeast   669 TSEISVVEDQLDHPRNMEKVSVSSGNSGLNPSQFY-----------------GSNNFRDNIASLT 716

  Fly   480 ------QKSVKNQKRIVRVQELMSSEEEKR--KSKQKAKLEHKQSK--LKQQSSIQTNNGRL 531
                  :|.::..:.::...:|.:::.:.:  |..|:..|:..:.|  ||||..:|.|...|
Yeast   717 ISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSL 778

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG8726NP_610341.2 PX_MONaKA 13..132 CDD:132781 29/149 (19%)
PKc 237..432 CDD:270622 47/303 (16%)
MDM1NP_013603.1 ATP-synt_I 6..>45 CDD:298845
PXA 85..276 CDD:214611 29/145 (20%)
RGS 462..567 CDD:295367 19/109 (17%)
PX_MDM1p 763..900 CDD:132786 7/17 (41%)
Nexin_C 993..1106 CDD:285792
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG2101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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