DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul1 and tnnt2

DIOPT Version :9

Sequence 1:	NP_523655.1	Gene:	Cul1 / 35742	FlyBaseID:	FBgn0015509	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_012809815.1	Gene:	tnnt2 / 100493699	XenbaseID:	XB-GENE-482614	Length:	279	Species:	Xenopus tropicalis

Alignment Length:	185	Identity:	36/185 - (19%)
Similarity:	67/185 - (36%)	Gaps:	35/185 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 RSLVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAF-----YEKESDAFLSTNTV 248
            :.:.:|:.|....:..:.|....|:::|....:..|.:........     .|||..|.::....
Frog    81 KRMEKDLTELQTLIEVHFESRKKEEEELQALTERMEKRRAERAEQLRIRNEREKERQARVAEERA 145

  Fly   249 TEYLKHVENRLEEETQRVRGF-NSKNGLSYLHETTADVLKSTCEE-----VLIEKHLKI------ 301
            .:..:....|.|::.::.:.| |..:...||.:|...|.|...|.     :|.|:...:
Frog   146 RKEEEENRKRAEDDVRKKKAFSNMLHFGGYLQKTERKVGKKQTEREKKKMILTERKTPLNIGNMN 210

  Fly   302 ---FHTEFQNLLNADRNDDLKRMYSLVALSSKNLTDLK------SILENHIL-HQ 346
               ..||.|:|.|        |:|.|.|....:....|      ::|.|.:. ||
Frog   211 EDKLRTEAQHLFN--------RIYELEAEKYDHQATFKKQKYEINVLRNRVSDHQ 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul1	NP_523655.1	Cullin	21..669	CDD:279260	36/185 (19%)
		CULLIN	454..593	CDD:214545
		Cullin_Nedd8	701..765	CDD:214883
tnnt2	XP_012809815.1	Troponin	81..215	CDD:279349	22/133 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900