DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1941 and MOGAT2

DIOPT Version :9

Sequence 1:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_011543569.1	Gene:	MOGAT2 / 80168	HGNCID:	23248	Length:	336	Species:	Homo sapiens

Alignment Length:	302	Identity:	117/302 - (38%)
Similarity:	170/302 - (56%)	Gaps:	24/302 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IEWAPKGVPMERRRQTFAMAFLILSFMILSFGSYFFVAAVLFYGSLLWRTIMVIYLVYVYANHKR 67
            :|:||..:|.|||.||.|:...:.||:.|:........|:||  :..| .:.|:|..:.|.:..:
Human     2 VEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLF--TRFW-LLTVLYAAWWYLDRDK 63

  Fly    68 THS----IMDGNGWKINRNNWLFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMG 128
            ...    |.....|.|    |  ::.:||||:.|||||||.|::|||....|||:|..|...|:.
Human    64 PRQGGRHIQAIRCWTI----W--KYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLC 122

  Fly   129 LDISKWLQLFPQVRPKVATLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGF 193
            .:.:.:..:||.:||.:..|...|..|..|..:.|.|||:..||:..::|          ||.|
Human   123 TESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHIL----------NRKG- 176

  Fly   194 TSNAVAILVGGAQEALDSHPGKYILTLKNRKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNS 258
            ..|.:.|:|||||||||:.||.:.|.|:||||||::|:..|:.:||.|||||.|:.||:.|...|
Human   177 GGNLLGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGS 241

  Fly   259 RVRRFQDFVKRITGISPLIPVGRGIFNYSFGFLPNRRRIVQV 300
            .:|..|:.:::|.|||..:..|||:|.||||.:|.||.|..|
Human   242 WLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	101/255 (40%)
MOGAT2	XP_011543569.1	LPLAT	41..297	CDD:302626	103/263 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146801
Domainoid	1	1.000	214	1.000	Domainoid score	I2726
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57020
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3400
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8637
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R305
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800